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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">rsp</journal-id><journal-title-group><journal-title xml:lang="ru">Научно-практическая ревматология</journal-title><trans-title-group xml:lang="en"><trans-title>Rheumatology Science and Practice</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1995-4484</issn><issn pub-type="epub">1995-4492</issn><publisher><publisher-name>IMA-PRESS, LLC</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14412/1995-4484-2004-806</article-id><article-id custom-type="elpub" pub-id-type="custom">rsp-943</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>Место сульфасалазина в комплексной терапии серонегатннных спондилоартритов</article-title><trans-title-group xml:lang="en"><trans-title>Place of sulfasalazine in complex treatment of seronegative spondylarthrities</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бадокин</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Badokin</surname><given-names>V V</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2004</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2004</year></pub-date><volume>42</volume><issue>4</issue><issue-title>№4 (2004)</issue-title><fpage>68</fpage><lpage>72</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Бадокин В.В., 2004</copyright-statement><copyright-year>2004</copyright-year><copyright-holder xml:lang="ru">Бадокин В.В.</copyright-holder><copyright-holder xml:lang="en">Badokin V.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://rsp.mediar-press.net/rsp/article/view/943">https://rsp.mediar-press.net/rsp/article/view/943</self-uri></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">&lt;div&gt;&lt;p&gt;Бадокин В.В., Агабабова Э.Р., Шубин С.В. Место глюкокортикостероидов в терапии серонегативных спон- дилоартритов. Научно-практическая ревматология, 2001, 4, 48-55&lt;/p&gt;&lt;p&gt;Насонова В.А., Насонов ЕЛ. Рациональная фармакотерапия ревматических заболеваний. М., Литтерра, 2003&lt;/p&gt;&lt;p&gt;Чепелева С.Н., Сигиднн Я.А., Лукина Г.В. Контролируемая оценка эффективности сульфасалазина при ан- килозирующем спондилоартрите. Научно-пракгич. ревматол., 2001, 4, 32-36&lt;/p&gt;&lt;p&gt;Altan L., Bingo! U., Karakos Y. et al. Clinical investigation of methotrexate in the treatment of ankylosing spondylitis. Scand. J. Rheumatol. 2001, 30, 255-259&lt;/p&gt;&lt;p&gt;Amor B. Data management in spondylarthropathies. Rheumatol, in Europe, 1996, 25, 92-95&lt;/p&gt;&lt;p&gt;Amor B., Dougados М., Kahn M.A. Management of refractory ankylosing spondylitis and related spondyloarthropathies. Rheum. Dis. North Am., 1995, 21, 117-126&lt;/p&gt;&lt;p&gt;Brandt J., Buss B., Sieper J., Braun.1. Efficacy of treatment with sulphasalazine versus azathioprine in ankylosing spondylitis. J. Rheumatol. 2000, 27, suppl. 59, 182-184&lt;/p&gt;&lt;p&gt;Braun J, Sieper J. Overview of the use of the anti-TNF agent infliximab in chronic inflammatory diseases. Expert Opin. Biol. Ther., 2003, 3, 141-168&lt;/p&gt;&lt;p&gt;Calin A., Tnurog J.D. Spondylarthritides. Oxford University Press, 1998&lt;/p&gt;&lt;p&gt;Clegg D.O., Reda D.J., Mejias E. et al. Comparison of sulphasalazine and placebo for the treatment of psoriatic arthritis and cutaneous psoriasis. Arthr. Rheum., 1996, 39, 2013-2020&lt;/p&gt;&lt;p&gt;Clegg D.O., Rede D.J., Weisman M.N. et al. Comparison of sulphasalazine and placebo in the treatment of reactive arthritis (Reiterys syndrome). A Department of Veterans Affairs Cooperative study. Arthr. Rheum., 1996, 39, 20212027&lt;/p&gt;&lt;p&gt;Clegg L.J., Reda D.J., Abdellatif M. Comparison of sulfasalazine for the treatment and placebo of axial and peripherial articular manifestations of the seronegative spondyloarthropathies. Arthr. Rheum., 1999. 42, 2325-2329&lt;/p&gt;&lt;p&gt;Combe B., Goupille P., Kuntz J.L. et al. Sulphasalazine in psoriatic arthritis: a randomized, multicentre, placebo-controlled study. Br. J. Rheumatol., 1996, 35, 664-668&lt;/p&gt;&lt;p&gt;Dougados М., Chaussade S. Treatment of inflammatory bowel disease-related arthropathies. Rheumatol, in Europe, 1997, 26,1, 27-30&lt;/p&gt;&lt;p&gt;Dougados М., Dormans B., Khan M. et al, Conventional treatments for ankylosing spondylitis. Ann. Rheum. Dis., 2002, 61. suppl. Ill, 40-50&lt;/p&gt;&lt;p&gt;Dougados М., Revel М., Khan M. Spondyloarthropathy treatment: progress in medical treatment, physical therapy and rehabilitation. Baillares Clin. Rheumatol., 1998, 12, 717-736&lt;/p&gt;&lt;p&gt;Dougados M.t van der Linden S., Leirisalo-Repo M. el al. Sulphasalazine in the treatment of spondylarthropathy. Arthr. Rheum., 1995, 38, 618-627&lt;/p&gt;&lt;p&gt;Egsmose C. Hansen Т., Andersen L.S. et al. Limited effect of sulphasalazine treatment in reactive arthritis. A ran нарастающей функциональной недостаточности опорнодвигательного аппарата. При периферической и ризомели- ческой формах идиопатического АС, ПА, протекающего с умеренной активностью воспаления, и особенно при арт- ропатиях, ассоциированных с хроническими воспалительными заболеваниями кишечника, сульфасалазин является препаратом, которому следует отдавать предпочтение перед другими болезнь-модифицируюшими средствами. domised double blind placebo controlled trial. Ann. Rheum. Dis., 1997, 56, 32-36&lt;/p&gt;&lt;p&gt;Ferraz M.B., Tugwell P., Goldsmith C.H., Atra E. Metaanalysis of sulphasalazine in ankylosing spondyliiis. J. Rheumatol., 1990, 17,1482-1486&lt;/p&gt;&lt;p&gt;Fraser S.М., Hopkins R., Hunter J.A. et al. Sulphasalazine in the management of psoriatic arthritis. Br. J. Rheumatol., 1993, 32, 923-925&lt;/p&gt;&lt;p&gt;Fuchs H.A. Use of sulphasalazine in rheumatic diseases. Bull. Rheum. Dis., 1997, 46. 3&lt;/p&gt;&lt;p&gt;Gladman D.D. Effictiveness of psoriatic arthritis. Sem, Arthr. Rheum., 2003, 33,1, 29-37&lt;/p&gt;&lt;p&gt;Goedcoop A.Y., Kraan M.C., Teunissen M.B.M. et al. Early effects of tumor necrosis factor a blocade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritis. Ann. Rheum. Dis., 2004, 63, 769-773&lt;/p&gt;&lt;p&gt;Gran J. Т., Husby G. Clinical, epidemiologic, and therapeutic aspects of ankylosing sponddylilis. Curr. Opin. Rheumatol., 1998, 10. 292-298&lt;/p&gt;&lt;p&gt;Gupta A.K., Grober J.S., Hamilton T.A. el ai. Sulphasalazine therapy for psoriatic arthritis: a double blend placebo controlled trial. J. Rheumatol., 1995, 22. 894-898&lt;/p&gt;&lt;p&gt;Hanauser S.B., Stathopoulos G. Risk-benefit assessment of drugs used in the treatment of inflammatory bowel disease. Drug Saf, 1991, 6, 192-219&lt;/p&gt;&lt;p&gt;Jones G., Crotty М., Brooks P. Interventions for treating psoriatic arthritis. Cochrane Database Syst. Rev., 2000, 3, CD0002I2.&lt;/p&gt;&lt;p&gt;Kahn V.V. Ankylosing spondylitis - the history of medical therapies. Clin. Exp. Rheumatol., 2002, 20, suppl.28, 3-5.&lt;/p&gt;&lt;p&gt;Kohler L., Kuipers J.G., Zeidler H. Managing seronegative spondarthritides. Rheumatol., 2000, 39, 360-368&lt;/p&gt;&lt;p&gt;McGonagle D., Khan M.A., Mazzo-Ortega H. -et al. Enlhesitis in spondyloarthritis. Curr. Opin. Rheumatol., 1999, II, 4, 244-250&lt;/p&gt;&lt;p&gt;Mease P. TNFa therapy in psoriatic arthritis and psoriasis, Ann. Rheum. Dis., 2004, 63, 755-758&lt;/p&gt;&lt;p&gt;Peppercorn M.A. Sulphasalazine: pharmacology, clinical use, toxicity and related new drug development. Ann, Intern. Med., 1984, 101, 377-386&lt;/p&gt;&lt;p&gt;Rahman P., Gladman D.D., Thorne J.C. et al. The use of sulphasalazine in psoriatic arthritis: a clinical experience. J. Rheumatol., 1998, 25, 1957-1961&lt;/p&gt;&lt;p&gt;Sieper J., Braun J., Rudwaleit M. et al. Ankylosing: an overview. Ann. Rheum. Dis. 2002. 61, suppl. III. 8-18.&lt;/p&gt;&lt;p&gt;Salvarani C., Macchioni P., Olivieri I. et al. A comparison of cyclosporine, sulphasalazine, and symptomatic therapy in the treatment of psoriatic arhritis. J. Rheumatol., 2001,28. 10, 2274-2282&lt;/p&gt;&lt;p&gt;Taggard A.J., Gardiner P.V., McEwoy F.M. et al. Which is the active moiety of sulphasalazine in ankylosing spondylitis? Arthr. Rheum., 1996, 39, 1400-1405&lt;/p&gt;&lt;p&gt;Veale D.J., FitzGerald O. Psoriatic arthritis - pathogenesis and epidemiology. Clin. Exp. Rheumatol., 2002. 20, 6, suppl. 28, 27-33&lt;/p&gt;&lt;p&gt;Ward M.M., Kuzis S. Treatment used by patients with ankylosing spondylitis: comparison with treatment preferences of rheumatologists. J. Clin. Rheunatol., 1999, 5, 1-8&lt;/p&gt;&lt;p&gt;Wolf R., Ruocco V. Triggered psoriasis. KheumayDerin 97,Malta, 1997&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation><mixed-citation xml:lang="en">&lt;div&gt;&lt;p&gt;Бадокин В.В., Агабабова Э.Р., Шубин С.В. Место глюкокортикостероидов в терапии серонегативных спон- дилоартритов. Научно-практическая ревматология, 2001, 4, 48-55&lt;/p&gt;&lt;p&gt;Насонова В.А., Насонов ЕЛ. Рациональная фармакотерапия ревматических заболеваний. М., Литтерра, 2003&lt;/p&gt;&lt;p&gt;Чепелева С.Н., Сигиднн Я.А., Лукина Г.В. Контролируемая оценка эффективности сульфасалазина при ан- килозирующем спондилоартрите. Научно-пракгич. ревматол., 2001, 4, 32-36&lt;/p&gt;&lt;p&gt;Altan L., Bingo! U., Karakos Y. et al. Clinical investigation of methotrexate in the treatment of ankylosing spondylitis. Scand. J. Rheumatol. 2001, 30, 255-259&lt;/p&gt;&lt;p&gt;Amor B. Data management in spondylarthropathies. Rheumatol, in Europe, 1996, 25, 92-95&lt;/p&gt;&lt;p&gt;Amor B., Dougados М., Kahn M.A. Management of refractory ankylosing spondylitis and related spondyloarthropathies. Rheum. Dis. North Am., 1995, 21, 117-126&lt;/p&gt;&lt;p&gt;Brandt J., Buss B., Sieper J., Braun.1. Efficacy of treatment with sulphasalazine versus azathioprine in ankylosing spondylitis. J. Rheumatol. 2000, 27, suppl. 59, 182-184&lt;/p&gt;&lt;p&gt;Braun J, Sieper J. Overview of the use of the anti-TNF agent infliximab in chronic inflammatory diseases. Expert Opin. Biol. Ther., 2003, 3, 141-168&lt;/p&gt;&lt;p&gt;Calin A., Tnurog J.D. Spondylarthritides. Oxford University Press, 1998&lt;/p&gt;&lt;p&gt;Clegg D.O., Reda D.J., Mejias E. et al. Comparison of sulphasalazine and placebo for the treatment of psoriatic arthritis and cutaneous psoriasis. Arthr. Rheum., 1996, 39, 2013-2020&lt;/p&gt;&lt;p&gt;Clegg D.O., Rede D.J., Weisman M.N. et al. Comparison of sulphasalazine and placebo in the treatment of reactive arthritis (Reiterys syndrome). A Department of Veterans Affairs Cooperative study. Arthr. Rheum., 1996, 39, 20212027&lt;/p&gt;&lt;p&gt;Clegg L.J., Reda D.J., Abdellatif M. Comparison of sulfasalazine for the treatment and placebo of axial and peripherial articular manifestations of the seronegative spondyloarthropathies. Arthr. Rheum., 1999. 42, 2325-2329&lt;/p&gt;&lt;p&gt;Combe B., Goupille P., Kuntz J.L. et al. Sulphasalazine in psoriatic arthritis: a randomized, multicentre, placebo-controlled study. Br. J. Rheumatol., 1996, 35, 664-668&lt;/p&gt;&lt;p&gt;Dougados М., Chaussade S. Treatment of inflammatory bowel disease-related arthropathies. Rheumatol, in Europe, 1997, 26,1, 27-30&lt;/p&gt;&lt;p&gt;Dougados М., Dormans B., Khan M. et al, Conventional treatments for ankylosing spondylitis. Ann. Rheum. Dis., 2002, 61. suppl. Ill, 40-50&lt;/p&gt;&lt;p&gt;Dougados М., Revel М., Khan M. Spondyloarthropathy treatment: progress in medical treatment, physical therapy and rehabilitation. Baillares Clin. Rheumatol., 1998, 12, 717-736&lt;/p&gt;&lt;p&gt;Dougados M.t van der Linden S., Leirisalo-Repo M. el al. Sulphasalazine in the treatment of spondylarthropathy. Arthr. Rheum., 1995, 38, 618-627&lt;/p&gt;&lt;p&gt;Egsmose C. Hansen Т., Andersen L.S. et al. Limited effect of sulphasalazine treatment in reactive arthritis. A ran нарастающей функциональной недостаточности опорнодвигательного аппарата. При периферической и ризомели- ческой формах идиопатического АС, ПА, протекающего с умеренной активностью воспаления, и особенно при арт- ропатиях, ассоциированных с хроническими воспалительными заболеваниями кишечника, сульфасалазин является препаратом, которому следует отдавать предпочтение перед другими болезнь-модифицируюшими средствами. domised double blind placebo controlled trial. Ann. Rheum. Dis., 1997, 56, 32-36&lt;/p&gt;&lt;p&gt;Ferraz M.B., Tugwell P., Goldsmith C.H., Atra E. Metaanalysis of sulphasalazine in ankylosing spondyliiis. J. Rheumatol., 1990, 17,1482-1486&lt;/p&gt;&lt;p&gt;Fraser S.М., Hopkins R., Hunter J.A. et al. Sulphasalazine in the management of psoriatic arthritis. Br. J. Rheumatol., 1993, 32, 923-925&lt;/p&gt;&lt;p&gt;Fuchs H.A. Use of sulphasalazine in rheumatic diseases. Bull. Rheum. Dis., 1997, 46. 3&lt;/p&gt;&lt;p&gt;Gladman D.D. Effictiveness of psoriatic arthritis. Sem, Arthr. Rheum., 2003, 33,1, 29-37&lt;/p&gt;&lt;p&gt;Goedcoop A.Y., Kraan M.C., Teunissen M.B.M. et al. Early effects of tumor necrosis factor a blocade on skin and synovial tissue in patients with active psoriasis and psoriatic arthritis. Ann. Rheum. Dis., 2004, 63, 769-773&lt;/p&gt;&lt;p&gt;Gran J. Т., Husby G. Clinical, epidemiologic, and therapeutic aspects of ankylosing sponddylilis. Curr. Opin. Rheumatol., 1998, 10. 292-298&lt;/p&gt;&lt;p&gt;Gupta A.K., Grober J.S., Hamilton T.A. el ai. Sulphasalazine therapy for psoriatic arthritis: a double blend placebo controlled trial. J. Rheumatol., 1995, 22. 894-898&lt;/p&gt;&lt;p&gt;Hanauser S.B., Stathopoulos G. Risk-benefit assessment of drugs used in the treatment of inflammatory bowel disease. Drug Saf, 1991, 6, 192-219&lt;/p&gt;&lt;p&gt;Jones G., Crotty М., Brooks P. Interventions for treating psoriatic arthritis. Cochrane Database Syst. Rev., 2000, 3, CD0002I2.&lt;/p&gt;&lt;p&gt;Kahn V.V. Ankylosing spondylitis - the history of medical therapies. Clin. Exp. Rheumatol., 2002, 20, suppl.28, 3-5.&lt;/p&gt;&lt;p&gt;Kohler L., Kuipers J.G., Zeidler H. Managing seronegative spondarthritides. Rheumatol., 2000, 39, 360-368&lt;/p&gt;&lt;p&gt;McGonagle D., Khan M.A., Mazzo-Ortega H. -et al. Enlhesitis in spondyloarthritis. Curr. Opin. Rheumatol., 1999, II, 4, 244-250&lt;/p&gt;&lt;p&gt;Mease P. TNFa therapy in psoriatic arthritis and psoriasis, Ann. Rheum. Dis., 2004, 63, 755-758&lt;/p&gt;&lt;p&gt;Peppercorn M.A. Sulphasalazine: pharmacology, clinical use, toxicity and related new drug development. Ann, Intern. Med., 1984, 101, 377-386&lt;/p&gt;&lt;p&gt;Rahman P., Gladman D.D., Thorne J.C. et al. The use of sulphasalazine in psoriatic arthritis: a clinical experience. J. Rheumatol., 1998, 25, 1957-1961&lt;/p&gt;&lt;p&gt;Sieper J., Braun J., Rudwaleit M. et al. Ankylosing: an overview. Ann. Rheum. Dis. 2002. 61, suppl. III. 8-18.&lt;/p&gt;&lt;p&gt;Salvarani C., Macchioni P., Olivieri I. et al. A comparison of cyclosporine, sulphasalazine, and symptomatic therapy in the treatment of psoriatic arhritis. J. Rheumatol., 2001,28. 10, 2274-2282&lt;/p&gt;&lt;p&gt;Taggard A.J., Gardiner P.V., McEwoy F.M. et al. Which is the active moiety of sulphasalazine in ankylosing spondylitis? Arthr. Rheum., 1996, 39, 1400-1405&lt;/p&gt;&lt;p&gt;Veale D.J., FitzGerald O. Psoriatic arthritis - pathogenesis and epidemiology. Clin. Exp. Rheumatol., 2002. 20, 6, suppl. 28, 27-33&lt;/p&gt;&lt;p&gt;Ward M.M., Kuzis S. Treatment used by patients with ankylosing spondylitis: comparison with treatment preferences of rheumatologists. J. Clin. Rheunatol., 1999, 5, 1-8&lt;/p&gt;&lt;p&gt;Wolf R., Ruocco V. Triggered psoriasis. KheumayDerin 97,Malta, 1997&lt;/p&gt;&lt;/div&gt;&lt;br /&gt;</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
