Stressors and depressive disorders in rheumatic diseases
https://doi.org/10.14412/1995-4484-2013-634
Abstract
The paper discusses the common comorbidity of immune inflammatory rheumatic diseases (RD) and depression. It considers the causes and mechanisms, which are common to these diseases, namely, the provocative role of chronic psychosocial stress; neuroendocrine dysregulations of an immune response, which give rise to the hyperproduction of the proinflammatory cytokines determining the magnitude of the major clinical syndromes of RD and depression — chronic pain, fatigue, sleep disorders, functional insufficiency. The impact of depression on patient treatment adherence and efficiency and the course and outcome of RD is discussed. Particular attention is given to the timely therapy of depression in RD, to the effect of genetically engineered biological agents on depressive symptomatology, to the need for a personified approach to prescribing antidepressants. By taking into account the importance of detection and treatment of depressive disorders in rheumatologic practice from the clinical standpoint and in terms of medical, social, and economic consequences, the author propose an interdisciplinary approach to managing the patients with RD with the participation of rheumatologists, psychiatrists, neurologists, and medical psychologists.
References
1. <div><p>Margaretten M., Julian L., Katz P., Yelin E. Depression in patients with rheumatoid arthritis: description, causes and mechanisms. Int J Clin Rheumtol 2011;6:617-23.</p><p>Thombs B.D., Taillefer S., Hudson M., Baron M. Depression in patients with systemic sclerosis: a systematic review of the evi dence. Arthr Rheum (Arthr Care Res) 2007;57:1089-97.</p><p>Kozora E., Ellison M.C., West S. Depression, fatigue, and pain in systemic lupus erythematosus (SLE): relationship to the American College of Rheumatology SLE neuropsychological battery. Arthr Rheum 2006;55:628-35.</p><p>Valtysdottir S.T., Gudbjornsson B., Lindqvist U. ct al. Anxiety and depression in patients with primary Sjogren's syndrome. J Rheumatol 2000;27:165-9.</p><p>Hanly J.G., Fisk J.D., McCurdy G. et al. Neuropsychiatric syndromes in patients with systemic lupus erythematosus and rheumatoid arthritis. J Rheumatol 2005;32:1459-66.</p><p>Вельтищев Д.Ю., Марченко А.С., Серавина О.Ф. и др. Аффективно-стрессовая модель депрессии: практическое внедрение в ревматологической практике. Психиатр психофармакотер 2009;11:17-22.</p><p>Zautra A.J., Parrish B.P., van Paymbroeck C.M. et al. Depression history, stress and pain in rheumatoid arthritis patients. J Behav Med 2007;30:187-97.</p><p>Bale T.L. Stress sensitivity and the development of affective disorders. Horm Behav 2006;50:529-33.</p><p>Лисицына Т.А., Вельтищев Д.Ю., Серавина О.Ф. и др. Психические расстройства у больных ревматоидным артритом. Науч-практич ревматол 2011;3:29-36.</p><p>Cohen P., Pine D.S., Must A. et al. Prospective association between somatic illness and mental illness from childhood to adulthood. Am J Epidemiol 1998;147:232-9.</p><p>Dube S.R., Fairweather D.L., Pearson W.S. et al. Cumulative childhood stress and autoimmune diseases in adults. Psychosom Med 2009;71:243-50.</p><p>Wegman H.L., Stetler C.A meta-analytic review of the effects of childhood abuse on medical outcomes in adulthood. Psychosom Med 2009;71:805-12.</p><p>Дрождина Е.Н., Ковалевская О.Б., Серавина О.Ф. и др. Роль психотравмирующих факторов в дезадаптации детей и подростков, страдающих ювенильным артритом. Соц клин психиатр 2012;1:44-50.</p><p>Smith R.S. The macrophage theory of depression. Med Hypotheses 1991;35:208-306.</p><p>Blackburn-Munro G. Hypothalamo-pituitary-adrenal axis dysfunction as a contributory factor to chronic pain and depression. Curr Pain Headache Rep 2004;8:116-24.</p><p>Haroon E., Raison Ch.L., Miller A.H. Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior. Neuropsychopharm Rev 2012;37:137-62.</p><p>Dowlati Y., Herrmann N., Swardfager W. et al. A meta-analysis of cytokines in major depression. Bio Psychiatry 2010;67:446-57.</p><p>Couzin-Frankel J. Inflammation bares a dark side. Science 2010;330:1621.</p><p>Strain J.J., Blumenfield M. Challenges for consultation-liaison psychiatry in the 21st century. Psychosomatic 2008;49:93-6.</p><p>Bair M.J., Robinson R.L., Katon W., Krocnke K. Depression and pain comorbidity. Arch Intern Med 2003;163:2433-45.</p><p>Blackburn-Munro G., Blackburn-Munro R.E. Chronic pain, chronic stress and depression: coincidence or consequence? J Neuroendocrin 2001;13:1009-23.</p><p>Lee Y.C., Chibnik L.B., Lu B. et al. The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional study. Arthr Res Ther 2009;11:R160.</p><p>Ramsey-Goldman R., Rothrock N. Fatigue in systemic lupus erythematosus and rheumatoid arthritis. Amer Acad Phys Med Rehabil 2010;2:384-92.</p><p>Campbell R.C.J., Batley M., Hammond A. et al. The impact of disease activity, pain, disability and treatments on fatigue in established rheumatoid arthritis. Clin Rheumatol 2012;31:717-22.</p><p>Repping-Wuts H., van Riel P., van Achterberg T. Fatigue in patients with rheumatoid arthritis: what is known and what is needed. Rheumatology 2009;48:207-9.</p><p>Novaes G.S., Perez M.O., Belardo M.B.B. et al. Correlation of fatigue with pain and disability in rheumatoid arthritis and osteoarthritis, respectively. Rev Bras Reumatol 2011;51: 447-55.</p><p>Stebbings S., Herbison P., Doyle T.C.H. et al. A comparison of fatigue correlates in rheumatoid arthritis and osteoarthritis: dispar ity in associations with disability, anxiety and sleep disturbance. Rheumatology 2010;49: 361-7.</p><p>Norheim K.B., Jonsson G., Omdal R. Biological mechanisms of chronic fatigue. Rheumatology 2011;50:1009-18.</p><p>American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th ed. Washington, DC: American Psychiatric Association, 2000.</p><p>Hoving J.L., Bartelds G.M., Sluiter J.K. et al. Perceived work ability, quality of life and fatigue in patients with rheumatoid arthritis after a 6-month course of TNF inhibitors: prospective intervention study and partial economic evaluation. Scand J Rheumatol 2009;38:246-50.</p><p>Feldman S.R., Gottlieb A.B., Bala M. et al. Infliximab improves health-related quality of life in the presence of comorbidities among patients with moderate-to-severe psoriasis. Br J Dermatol 2008;159:704-10.</p><p>Uguz F., Akman C., Kucuksarac S., Tufekci O. Anti-tumor necrosis factor-alpha therapy is associated with less frequent mood and anxiety disorders in patients with rheumatoid arthritis. Psychiatry Clin Neurosci 2009;63:50-5.</p><p>Ertenli I., Ozer S., Kiraz S. et al. Infliximab, a TNF-α antagonist treatment in patients with ankylosing spondylitis: the impact on depression, anxiety and quality of life level. Rheumatol Int 2012;32:323-30.</p><p>Moreland L.W., Genovese M.C., Sato R., Singh A. Effect of etanercept on fatigue in patients with recent or established rheumatoid arthritis. Arthr Rheum (Arthr Care Res) 2006;55:287-93.</p><p>Wolf F., Michaud K. Fatigue, rheumatoid arthritis and anti-tumor necrosis factor therapy: an investigation in 24831 patients. J Rheumatol 2004;31:2115-20.</p><p>Chauffier K., Salliot C., Berenbaum F., Sellam J. Effect of biotherapies on fatigue in rheumatoid arthritis: a systematic review of the literature and meta-analysis. Rheumatology (Oxford) 2012;51:60-8.</p><p>Van Hoogmoed D., Fransen J., Bleijenberg G., van Riel P. Physical and psychosocial correlates of severe fatigue in rheumatoid arthritis. Rheumatology 2010;49:1294-302.</p><p>Hider S.L., Tanveer W., Brownfield A. et al. Depression in RA patients treated with anti-TNF is common and under-recognized in the rheumatology clinic. Rheumatology 2009;48:1152-4.</p><p>Griffin W.S.T. Perispinal etanercept: Potential as an Alzheimer therapeutic. J Neuroinflamm 2008;5:3.</p><p>Tobinick E.L., Gross H. Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. J Neuroinflamm 2008;5:2.</p><p>Castanon N., Leonard B.E., Neveu PJ., Yirmiya R. Effects of antidepressants on cytokine production and actions. Brain Behav Immun 2002;16:569-74.</p><p>Janssen D.G.A., Caniato R.N., Verster J.C., Baune B.T. A psy-choneuroimmunological review on cytokines involved in antidepressant treatment response. Hum Psychopharm Clin Exp 2010;25:201-15.</p><p>Fitzgerald P., O’Brien S.M., Scully P. et al. Cutaneous glucocorticoid receptor sensitivity and pro-inflammatory cytokine levels in antidepressant-resistant depression. Psychol Med 2006;36:37-43.</p><p>Leonard B.E., Myint A. The psychoneuroimmunology of depression. Hum Psychopharm Clin Exp 2009;24:165-75.</p><p>Sleath B., Chewning B., de Vellis B.M. et al. Communication about depression during rheumatoid arthritis patient visits. Arthr Rheum 2008;59:186-91.</p><p>Ang D.C., Choi H., Kroenke K., Wolfe F. Comorbid depression is an independent risk factor for mortality in patients with rheumatoid arthritis. J Rheumatol 2005;32:1013-9.</p><p>DiMatteo M.R., Lepper H.S., Croghan T.W. Depression is a risk factor for noncompliance with medical treatment. Arch Intern Med 2000;160:2101-7.</p><p>Treharne G.J., Lyons A.C., Kitas G.D. Suicidal ideation in patients with rheumatoid arthritis. Research may help identify patients at high risk. Br Med J 2000;32:1290.</p></div><br />
Review
For citations:
Lisitsyna T.A., Veltishchev D.Yu., Nasonov E.L. Stressors and depressive disorders in rheumatic diseases. Rheumatology Science and Practice. 2013;51(2):98-103. (In Russ.) https://doi.org/10.14412/1995-4484-2013-634
Views:
1200
Email this article 