AN EPIDEMIOLOGICAL SURVEY OF OSTEOPOROTIC FRACTURES IN OLDER RESIDENTS FROM THE MIDDLE URALS
https://doi.org/10.14412/1995-4484-2014-643-649
Abstract
The epidemiological characteristics of osteoporotic fractures in Russia have been inadequately studied.
Objective: to estimate the incidence rate of osteoporotic fractures in the old age groups of an urban population in the Middle Urals.
Subjects and methods. The survey was performed in Pervouralsk, a typical industrial town in the Middle Urals, with a total of 160,860 people, including 54,189 dwellers over 50 years of age (20,746 men and 33,443 women), which amounted to 33.7% of the general population of the town. The survey covered its residents aged 50 years and over who had fractures of the proximal hip (FPH), distal forearm (FDF), distal shin, ribs, or surgical neck of the humerus
between 1 January 2008 and 31 December 2009. Statistical analysis was made applying the programs Biostatistics, Microsoft Excell 2007, and MedCalc (demo-version). The findings were processed using parametric and nonparametric statistical methods.
Results. During two years, 1371 fractures, including FPH, FDF, fractures of the humerus, distal shin, and ribs, were registered in the examined sample of persons aged 50 years and over from Pervouralsk. 383 (27.9%) of these fractures occurred in men and 988 (72.1%) in women. The incidence rate of all fractures was 1265.0 per 100,000 inhabitants aged 50 years and over (1,477.1 for women and 923.1 for men). FDF were more common in women, the incidence was 787.9 cases per 100,000 population; costal fractures – in men (386.7 per 100,000). The investigation has shown that certain types of fractures are predominant in the oldest age groups. Thus, the incidence rate of FDF and fractures of the distal shin decreases while that of FPH and fractures of the humerus increases
with age, which is likely to be due to several causes: an age-related decline in bone mass; an increase in the frequency of falls with age; muscle weakness and movement discoordination, which alter the mechanism of fall and increase the risk of femoral and humeral fractures.
About the Authors
E. N. Gladkova
Ural State Medical University, Ministry of Health of Russia, Ekaterinburg, Russia 3, Repin St., Yekaterinburg 620000
Russian Federation
Russian Federation
V. N. Khodyrev
Ural State Medical University, Ministry of Health of Russia, Ekaterinburg, Russia 3, Repin St., Yekaterinburg 620000
Russian Federation
Russian Federation
O. M. Lesnyak
Ural State Medical University, Ministry of Health of Russia, Ekaterinburg, Russia 3, Repin St., Yekaterinburg 620000
Russian Federation
Russian Federation
References
1. Беневоленская ЛИ, редактор. Эпидемиология остеопороза и переломов: Руководство по остеопорозу. Москва: БИНОМ; 2003. С. 10–54. [Benevolenskaya LI, editor. Epidemiologiya osteoporoza i erelomov: Rukovodstvo po osteoporozu [Epidemiology of osteoporosis and changes: Guide to osteoporosis]. Moscow: BINOM; 2003. P. 10–54.
2. Kanis JA, Johnell O, Oden A, et al. FRAX ™ and the assessment of fracture probability in men and women from the UK. Osteoporos Int. 2008;19:385–97. DOI: http://dx.doi.org/10.1007/s00198-007- 0543-5.
3. Михайлов ЕЕ, Беневоленская ЛИ, Аникин СГ и др. Частота переломов проксимального отдела бедренной кости и дистального отдела предплечья среди городского населения России. Остеопороз и остеопатии. 1999;(3):2–6. [Mikhailov EE, Benevolenskaya LI, Anikin SG, et al. Frequency of changes of proximal department of a femur and distalny department of a forearm among urban population of Russia. Osteoporoz i osteopatii. 1999;(3):2–6. (In Russ.)]
4. Johnel O, Gullberg B, Allander E, et al.; MEDOS Study Group. The apparent incidence of hip fracture in Europe: a study of national register sources. Osteoporos Int. 1992;2(6):298–302. DOI: http://dx.doi.org/10.1007/BF01623186.
5. Лесняк ОМ. Аудит состояния проблемы остеопороза в странах Восточной Европы и Центральной Азии 2010. Остеопороз и остеопатии. 2011;(2):3–6. [Lesnyak OM. Audit of a condition of a problem of osteoporosis in countries of Eastern Europe and Central Asia 2010. Osteoporoz i osteopatii. 2011;(2):3–6. (In Russ.)]
6. Lim S, Koo BK, Lee EJ, et al. Incidence of hip fractures in Korea. J Bone Miner Metab. 2008;26:400–5. DOI: http://dx.doi.org/10.1007/s00774-007-0835-z.
7. Chevalley T, Guilley E, Herrmann FR, et al. Incidence of hip fracture over a 10-year period (1991–2000): reversal of a secular trend. Bone. 2007;40:1284–9. DOI: http://dx.doi.org/10.1016/j.bone.2006.12.063.
8. Pentek M, Horvath C, Boncz I, et al. Epidemiology of osteoporosis related fractures in Hungary from the nationwide health insurance database, 1999–2003. Osteoporos Int. 2008;19(2):243–9. DOI: http://dx.doi.org/10.1007/s00198-007-0453-6.
9. Boereboom FTJ, de Groot RRM, Raymakers JA, et al. The incidence of hip fractures in the Netherlands. Netherlands J Med. 1991;38:51–8.
10. Koh LKН, Saw SM, Lee JJM, et al. National Working Committee on Osteoporosis. Hip fracture incidence rates in Singapore 1991–1998. Osteoporos Int. 2001;12(4):311–8. DOI: http://dx.doi.org/10.1007/s001980170121.
11. Kanis JA, Johnell O, Oden A, et al. Long-term risk of osteoporosis fracture in Malmo. Osteoporos Int. 2000;11:669–74. DOI: http://dx.doi.org/10.1007/s001980070064.
12. Crawford JR, Parker MJ. Seasonal variation of proximal femoral fractures in the United Kingdom. Injury. 2003;34(3):223–5. DOI: http://dx.doi.org/10.1016/S0020-1383(02)00211-5.
13. Chesser TJ, Howlett I, Ward AJ, et al. The influence of outside temperature and season on the incidence of hip fractures in patients over the age of 65. Age and Ageing. 2002;31(5):343–8. DOI: http://dx.doi.org/10.1093/ageing/31.5.343.
14. Melton LJ 3rd, Amadio PC, Crowson CS, et al. Long-term trends in the incidence of distal forearm fractures. Osteoporos Int. 1998;8:341–8. DOI: http://dx.doi.org/10.1007/s001980050073.
15. EPOS Group. Incidence of limb fracture across Europe: results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int. 2002;13:565–71. DOI: http://dx.doi.org/10.1007/s001980200074.
16. Melton LJ 3rd. Epidemiology of fractures. In: Osteoporosis: etiology, diagnosis and management, 2nd ed. Philadelphia: Lippincott-Raven; 1995. P. 225–47.
17. Endres HG, Dasch B, Lungenhausen M, et al. Patients with femoral or distal forearm fracture in Germany: a prospective observational study on health care situation and outcome. BMC Public Health. 2006;6:87. DOI: http://dx.doi.org/10.1186/1471-2458-6-87.
18. Brogren E, Petranek M, Atroshi I. Incidence and characteristics of distal radius fractures in a southern Swedish region. BMC Musculoskelet Disord. 2007;8:48. DOI: http://dx.doi.org/10.1186/1471-2474-8-48.
19. Kanis JA, Johnell O, Oden A, et al. The burden of osteoporotic fractures: a method for setting intervention thresholds. Osteoporos Int. 2000;12:417–27. DOI: http://dx.doi.org/10.1007/s001980170112.
20. Wildner M, Clark DE. Hip fracture incidence in East and West Germany: reassessment ten years after Unification. Osteoporos Int. 2001;12:136–9. DOI: http://dx.doi.org/10.1007/s001980170146.
21. WHO Scientific Group on the Burden of Muskuloskeletal Conditions at the Start of the New Millenium. The burden of muskuloskeletal conditions at the start of the new millennium. Geneva. World Health Organ Tech Rep Ser. 2003;919:1–218.
22. Lippuner K, von Overbeck J, Perrelet R, et al. Incidence and direct medical costs of hospitalizations due to osteoporotic fractures in Sweden. Osteoporos Int. 1997;7:414–25. DOI: http://dx.doi.org/10.1007/PL00004149.
23. Sanders KM, Nicholson GC, Ugoni AM, et al. Heath burden of hip in other fractures in Australia beyond 2000: projections based on the Geelong Osteoporosis Study. Med J Aust. 1999;170:467–70.
24. Sanders KM, Seeman E, Ugoni AM, et al. Age and gender specific rate of fractures in Australia: a population based study. Osteoporos Int. 1999;10:240–7. DOI: http://dx.doi.org/10.1007/s001980050222.
25. Melton LJ 3rd, Cooper C. Magnitude and impact of osteoporosis and fractures. In: Osteoporosis. 2nd ed. Vol.1. San Diego: Academic Press; 2001. P. 557–67.
Review
For citations:
Gladkova E.N., Khodyrev V.N., Lesnyak O.M. AN EPIDEMIOLOGICAL SURVEY OF OSTEOPOROTIC FRACTURES IN OLDER RESIDENTS FROM THE MIDDLE URALS. Rheumatology Science and Practice. 2014;52(6):643-649. (In Russ.) https://doi.org/10.14412/1995-4484-2014-643-649
Views:
941
Email this article 