Цертолизумаба пэгол в лечении аксиального спондилоартрита
https://doi.org/10.14412/1995-4484-2015-641-645
Аннотация
Представлены результаты исследования RAPID-axSpA, в котором впервые оценивалась эффективность ингибитора фактора некроза опухоли α (ФНОα) цертолизумаба пэгола (ЦЗП) при клинических вариантах аксиального спондилоартрита (аксСпА): уже развившемся анкилозирующем спондилите и нерентгенологическом аксСпА. Показано, что ЦЗП эффективен при всех формах аксСпА, вне зависимости от того, имеются ли структурные (рентгенологически выявляемые) повреждения крестцово-подвздошных суставов или они отсутствуют. Также данное исследование впервые показало длительную эффективность ингибиторов ФНОα у пациентов, изначально имеющих высокий уровень С-реактивного белка и/или признаки активного сакроилиита на магнитно-резонансной томограмме.
Об авторе
Ш. Ф. ЭрдесРоссия
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Рецензия
Для цитирования:
Эрдес Ш.Ф. Цертолизумаба пэгол в лечении аксиального спондилоартрита. Научно-практическая ревматология. 2015;53(6):641-645. https://doi.org/10.14412/1995-4484-2015-641-645
For citation:
Erdes Sh.F. CERTOLIZUMAB PEGOL IN THE TREATMENT OF AXIAL SPONDYLOARTHRITIS. Rheumatology Science and Practice. 2015;53(6):641-645. (In Russ.) https://doi.org/10.14412/1995-4484-2015-641-645