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PROBLEMS IN THE THERAPY OF AXIAL SPONDYLOARTHRITIS IN THE PROCEEDINGS OF THE EULAR CONGRESS 2015 (ROME, 10–13 JUNE 2015)

https://doi.org/10.14412/1995-4484-2016-1S-83-86

Abstract

The Congress considered the issues pertinent  to the latest approaches to therapy for axial spondyloarthritis  (axSpA), as well as the problems associated with a search for axSpA-modifying anti-rheumatic drugs. Reports on the results of therapy with nonsteroidal  anti-inflammatory drugs and biological agents (tumor necrosis factor-α  and interleukin 17/23 inhibitors) were of the most relevance.

About the Authors

O. A. Rumyantseva
V.A. Nasonova Research Institute of Rheumatology, Moscow
Russian Federation
Rumyantseva Oksana


Sh. F. Erdes
V.A. Nasonova Research Institute of Rheumatology, Moscow
Russian Federation


References

1. В тексте в квадратных скобках с буквенно-цифровой аббревиатурой указаны ссылки на тезисы в журнале Annals of the Rheumatic Diseases, June 2015; Volume 74 Supplement 2.

2. Haroon N, Inman RD, Learch TJ, et al. The impact of tumor necrosis factor α inhibitors on radiographic progression in ankylosing spondylitis. Arthritis Rheum. 2013;65(10):2645-54. doi: 10.1002/art.38070

3. Song IH, Hermann K, Haibel H, et al. Effects of etanercept versus sulfasalazine in early axial spondyloarthritis on active inflammatory lesions as detected by whole-body MRI (ESTHER): a 48-week randomised controlled trial. Ann Rheum Dis. 2011;70(4):590-6. doi: 10.1136/ard.2010.139667

4. Wanders A, van der Heijde D, Landewe R, et al. Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial. Arthritis Rheum. 2005;52(6):1756-65. doi: 10.1002/art.21054

5. Baeten D, Braun J , Baraliakos X, et al. Secukinumab, a Monoclonal Antibody to Interleukin-17A, Significantly Improves Signs and Symptoms of Active Ankylosing Spondylitis: Results of a 52-Week Phase 3 Randomized Placebo-Controlled Trial with Intravenous Loading and Subcutaneous Maintenance Dosing. Arthritis Rheum. 2014;66(Suppl):S360.

6. Poddubnyy D, Hermann KG, Callhoff J, et al. Ustekinumab for the treatment of patients with active ankylosing spondylitis: results of a 28-week, prospective, open-label, proof-of-concept study (TOPAS). Ann Rheum Dis. 2014; 73(5):817-23. doi: 10.1136/annrheumdis-2013-204248

7. Song IH, Hermann KG, Haibel H, et al. Relationship between active inflammatory lesions in the spine and sacroiliac joints and new development of chronic lesions on whole-body MRI in early axial spondyloarthritis: results of the ESTHER trial at week 48. Ann Rheum Dis. 2011;70(7):1257-63. doi: 10.1136/ard.2010.147033

8. Maksymowych WP, Morency N, Conner-Spady B, Lambert RG. Suppression of inflammation and effects on new bone formation in ankylosing spondylitis: evidence for a window of opportunity in disease modification. Ann Rheum Dis. 2013; 72(1):23-8. doi: 10.1136/annrheumdis-2011-200859

9. Glintborg B, Ostergaard M, Krogh NS, et al. Clinical response, drug survival, and predictors thereof among 548 patients with psoriatic arthritis who switched tumor necrosis factor α inhibitor therapy: results from the Danish Nationwide DANBIO Registry. Arthritis Rheum. 2013 May;65(5):1213-23. doi: 10.1002/art.37876

10. Glintborg B, Ostergaard M, Krogh NS, et al. Clinical response, drug survival and predictors thereof in 432 ankylosing spondylitis patients after switching tumour necrosis factor α inhibitor therapy: results from the Danish nationwide DANBIO registry. Ann Rheum Dis. 2013 Jul;72(7):1149-55. doi: 10.1136/annrheumdis-2012-201933.


Review

For citations:


Rumyantseva O.A., Erdes Sh.F. PROBLEMS IN THE THERAPY OF AXIAL SPONDYLOARTHRITIS IN THE PROCEEDINGS OF THE EULAR CONGRESS 2015 (ROME, 10–13 JUNE 2015). Rheumatology Science and Practice. 2016;54(1S):83-86. (In Russ.) https://doi.org/10.14412/1995-4484-2016-1S-83-86

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)