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The reaction of the skin and its appendages in rheumatoid arthritis patients using subcutaneous methotrexate: A description of three cases

https://doi.org/10.14412/1995-4484-2016-478-481

Abstract

The paper reports the development of the adverse events of the skin and its appendages due to subcutaneous methotrexate, which serve as a manifestation of its toxicity in patients with rheumatoid arthritis. It discusses the possible mechanisms of their occurrence, although both clinical presentations and histological changes are not specific. 

About the Authors

Yu. V. Muravyev
V.A. Nasonova Research Institute of Rheumatology, Moscow
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522


G. I. Gridneva
V.A. Nasonova Research Institute of Rheumatology, Moscow
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522


S. G. Radenska-Lopovok
V.A. Nasonova Research Institute of Rheumatology, Moscow
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522


N. I. Kharitonova
Federal Medical Center, Russian Federal Property Management Agency, Moscow
Russian Federation
31, Kalanchevskaya Street, Moscow 107078


References

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Review

For citations:


Muravyev Yu.V., Gridneva G.I., Radenska-Lopovok S.G., Kharitonova N.I. The reaction of the skin and its appendages in rheumatoid arthritis patients using subcutaneous methotrexate: A description of three cases. Rheumatology Science and Practice. 2016;54(4):478-481. (In Russ.) https://doi.org/10.14412/1995-4484-2016-478-481

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)