Системная красная волчанка с ювенильным дебютом: особенности клинической картины и современные подходы к диагностике
Аннотация
Системная красная волчанка (СКВ) – аутоиммунное заболевание с вовлечением в патологический процесс различных органов и систем, непрогнозируемым течением, риском развития жизнеугрожающих состояний, которое в 10–20% случаев дебютирует в детском и подростковом возрасте. Начало СКВ до наступления совершеннолетия влияет на клинические проявления, особенности течения и прогноз. На основе анализа данных литературы в статье анализируются особенности дебюта и клинической картины СКВ у детей и подростков, обсуждаются аспекты верификации диагноза с учетом необходимости раннего назначения эффективной персонифицированной терапии и улучшения прогноза.
Об авторах
М. И. Каледа
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия
Россия
старший научный сотрудник лаборатории ревматических заболеваний детского возраста с реабилитационной группой ФГБНУ НИИР им. В.А. Насоновой, канд. мед. наук
Москва, Россия 115522 Москва, Каширское шоссе, 34А
И. П. Никишина
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия
Россия
заведующая лабораторией ревматических заболеваний детского возраста с реабилитационной группой ФГБНУ НИИР им. В.А. Насоновой, канд. мед. наук
Москва, Россия 115522 Москва, Каширское шоссе, 34А
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Для цитирования:
Каледа М.И., Никишина И.П. Системная красная волчанка с ювенильным дебютом: особенности клинической картины и современные подходы к диагностике. Научно-практическая ревматология. 2017;55(5):526-535. https://doi.org/10.14412/1995-4484-2017-526-535
For citation:
Kaleda M.I., Nikishina I.P. JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL FEATURES AND CURRENT DIAGNOSTIC APPROACHES. Rheumatology Science and Practice. 2017;55(5):526-535. (In Russ.) https://doi.org/10.14412/1995-4484-2017-526-535
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