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Prevention of arthritis attacks in the use of urate-lowering therapy in patients with gout

https://doi.org/10.14412/1995-4484-2018-760-766

Abstract

During the first months after initiation of urate-lowering therapy in patients with gout, the risk of exacerbating arthritis substantially increases, frequently causing them to refuse this treatment. The main way to avoid this risk is the preventive administration of colchicine, nonsteroidal anti-inflammatory drugs, or glucocorticoids. This prevention of arthritis attacks is stipulated in the latest versions of many national and international guidelines; nevertheless, this tactic is rarely used in practice. The review presents the most significant studies on this problem.

About the Author

M. N. Chikina
V.A. Nasonova Research Institute of Rheumatology.
Russian Federation

34A, Kashirskoe Shosse, Moscow, 115522.



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For citations:


Chikina M.N. Prevention of arthritis attacks in the use of urate-lowering therapy in patients with gout. Rheumatology Science and Practice. 2018;56(6):760-766. (In Russ.) https://doi.org/10.14412/1995-4484-2018-760-766

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)