По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии
https://doi.org/10.14412/1995-4484-2019-496-510
Аннотация
Многообразие клинических проявлений системной красной волчанки (СКВ), волнообразное течение с чередованием ремиссий и обострений делают это заболевание одним из наиболее трудных для диагностики, лечения и оценки эффективности терапии.
Несмотря на то что разработанные в последние годы методы ранней диагностики, способы применения комбинированной патогенетической терапии и мониторинга течения болезни привели к увеличению выживаемости (≥90%) и продолжительности жизни пациентов с СКВ, остается еще много нерешенных проблем. В частности, эффективность лечения СКВ пока не достаточна и полностью контролировать активность заболевания удается нечасто. Рецидивирующее течение СКВ в сочетании с коморбидной патологией, а также неблагоприятным воздействием глюкокортикоидов (ГК) и иммуносупрессантов способствует накоплению необратимых органных повреждений.
Статья посвящена обзору обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению СКВ, которые были опубликованы в 2019 г. Представлены комментарии и дискуссионные вопросы с учетом российских рекомендаций по лечению СКВ.
Об авторах
Т. В. ПопковаРоссия
Попкова Татьяна Валентиновна.
115522, Москва, Каширское шоссе, 34А.
Т. А. Панафидина
Россия
115522, Москва, Каширское шоссе, 34А.
С. К. Соловьев
Россия
115522, Москва, Каширское шоссе, 34А.
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Рецензия
Для цитирования:
Попкова Т.В., Панафидина Т.А., Соловьев С.К. По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии. Научно-практическая ревматология. 2019;57(5):496-510. https://doi.org/10.14412/1995-4484-2019-496-510
For citation:
Popkova T.V., Panafidina T.A., Solovyev S.K. According to the 2019 updated European League Against Rheumatism (EULAR) recommendations for the treatment of systemic lupus erythematosus: debatable issues and comments. Rheumatology Science and Practice. 2019;57(5):496-510. (In Russ.) https://doi.org/10.14412/1995-4484-2019-496-510