По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии
Аннотация
Многообразие клинических проявлений системной красной волчанки (СКВ), волнообразное течение с чередованием ремиссий и обострений делают это заболевание одним из наиболее трудных для диагностики, лечения и оценки эффективности терапии.
Несмотря на то что разработанные в последние годы методы ранней диагностики, способы применения комбинированной патогенетической терапии и мониторинга течения болезни привели к увеличению выживаемости (≥90%) и продолжительности жизни пациентов с СКВ, остается еще много нерешенных проблем. В частности, эффективность лечения СКВ пока не достаточна и полностью контролировать активность заболевания удается нечасто. Рецидивирующее течение СКВ в сочетании с коморбидной патологией, а также неблагоприятным воздействием глюкокортикоидов (ГК) и иммуносупрессантов способствует накоплению необратимых органных повреждений.
Статья посвящена обзору обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению СКВ, которые были опубликованы в 2019 г. Представлены комментарии и дискуссионные вопросы с учетом российских рекомендаций по лечению СКВ.
Об авторах
Т. В. Попкова
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия
Россия
Попкова Татьяна Валентиновна.
115522, Москва, Каширское шоссе, 34А.
Т. А. Панафидина
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия
Россия
115522, Москва, Каширское шоссе, 34А.
С. К. Соловьев
Научно-исследовательский институт ревматологии им. В.А. Насоновой
Россия
Россия
115522, Москва, Каширское шоссе, 34А.
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Для цитирования:
Попкова Т.В., Панафидина Т.А., Соловьев С.К. По материалам обновленных рекомендаций Европейской антиревматической лиги (EULAR) по лечению системной красной волчанки – 2019: дискуссионные вопросы и комментарии. Научно-практическая ревматология. 2019;57(5):496-510. https://doi.org/10.14412/1995-4484-2019-496-510
For citation:
Popkova T.V., Panafidina T.A., Solovyev S.K. According to the 2019 updated European League Against Rheumatism (EULAR) recommendations for the treatment of systemic lupus erythematosus: debatable issues and comments. Rheumatology Science and Practice. 2019;57(5):496-510. (In Russ.) https://doi.org/10.14412/1995-4484-2019-496-510
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