Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus
https://doi.org/10.47360/1995-4484-2020-437-442
Abstract
Neuropsychiatric disorders in juvenile-onset systemic lupus erythematosus (SLE) stay in the focus of attention in recent decades due to significant influence of CNS lesions on SLE course in general, necessity to optimize therapeutic interventions and outline prognosis. This paper considers the prevalence of neurolupus in children and adolescents, specific features of the clinical picture, possible relationships with other SLE manifestations and immunological disorders, aspects of neuropsychiatric disorders pathogenesis and potential influence of growing and developing nervous system on SLE course, resulting in varying neurolupus manifestations and prognosis.
About the Authors
M. I. Kaleda
VA Nasonova Research Institute of Rheumatology
Russian Federation
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
I. P. Nikishina
VA Nasonova Research Institute of Rheumatology
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
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Kaleda M.I., Nikishina I.P. Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus. Rheumatology Science and Practice. 2020;58(4):437-442. (In Russ.) https://doi.org/10.47360/1995-4484-2020-437-442
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