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Work disability in systemic sclerosis – What is known?

https://doi.org/10.47360/1995-4484-2023-672-677

Abstract

The medical and social significance of systemic sclerosis (SSc) is high. The progressive disease has a significant impact on the functional status, work participation and leads to early disability in patients of working age. The article presents data on the prevalence of work disability in patients with SSc in comparison with other rheumatic diseases, the frequency of separation from work and work transitions due to the problems connected with SSc, the socio-economic burden of SSc in different countries. The article specifies the components of the disease which affect the ability to work, the main approaches to quantify the indicators of working ability, describes the instruments most commonly used for this purpose. The data of various authors on working ability measurement and predictors of work disability in patients with SSc are presented.

About the Authors

A. A. Klimenko
N.I. Pirogov Russian National Research Medical University
Russian Federation

Alesya A. Klimenko.

117997, Moscow, Ostrovitianova str., 1


Competing Interests:

None



E. P. Mikheeva
N.I. Pirogov Russian National Research Medical University
Russian Federation

Ekaterina P. Mikheeva.

117997, Moscow, Ostrovitianova str., 1


Competing Interests:

None



N. A. Shostak
N.I. Pirogov Russian National Research Medical University
Russian Federation

Nadezhda A. Shostak.

117997, Moscow, Ostrovitianova str., 1


Competing Interests:

None



N. A. Demidova
N.I. Pirogov Russian National Research Medical University
Russian Federation

Natalia A. Demidova.

117997, Moscow, Ostrovitianova str., 1


Competing Interests:

None



References

1. Singh MK, Clements PJ, Furst DE Maranian P, Khanna D. Work productivity in scleroderma: analysis from the University of California, Los Angeles scleroderma quality of life study. Arthritis Care Res (Hoboken). 2012;64(2):176-183. doi: 10.1002/acr.20676

2. Hudson M, Steele R, Lu Y, Thombs BD; Canadian Scleroderma Research Group; Baron M. Work disability in systemic sclerosis. J Rheumatol. 2009;36(11):2481-2486. doi: 10.3899/jrheum.081237

3. Lee JJY, Gignac MAM, Johnson SR. Employment outcomes in systemic sclerosis. Best Pract Res Clin Rheumatol. 2021;35(3):101667. doi: 10.1016/j.berh.2021.101667

4. Ouimet JM, Pope JE, Gutmanis I, Koval J. Work disability in scleroderma is greater than in rheumatoid arthritis and is predicted by high HAQ scores. Open Rheumatol J. 2008;2:44-52. doi: 10.2174/1874312900802010044

5. Mau W, Listing J, Huscher D, Zeidler H, Zink A. Employment across chronic inflammatory rheumatic diseases and comparison with the general population. J Rheumatol. 2005;32(4):721-728.

6. Morrisroe K, Sudararajan V, Stevens W, Sahhar J, Zochling J, Roddy J, et al. Work productivity in systemic sclerosis, its economic burden and association with health-related quality of life. Rheumatology (Oxford). 2018;57(1):73-83. doi: 10.1093/rheumatology/kex362

7. Klabukova DL, Krysanova VS, Ermolaeva TN, Davydovskaya MV, Kokushkin KA. Economic burden of systemic sclerosis: Systematic review. Farmakoekonomika. Modern Pharmacoeconomics and Pharmacoepidemiology. 2020;13(3):291-303 (In Russ.). doi: 10.17749/2070-4909/farmakoekonomika.2020.041

8. Knarborg M, Løkke A, Hilberg O, Ibsen R, Sikjaer MG. Direct and indirect costs of systemic sclerosis and associated interstitial lung disease: A nationwide population-based cohort study. Respirology. 2022;27(5):341-349. doi: 10.1111/resp.14234

9. Xiang L, Kua SMY, Low AHL. Work productivity and economic burden of systemic sclerosis in a multiethnic Asian population. Arthritis Care Res (Hoboken). 2022;74(5):818-827. doi: 10.1002/acr.24521

10. Padala SD, Lao C, Solanki K, White D. Direct and indirect health-related costs of systemic sclerosis in New Zealand. Int J Rheum Dis. 2022;25(12):1386-1394. doi: 10.1111/1756-185X.14433

11. Sandqvist G, Scheja A, Hesselstrand R. Pain, fatigue and hand function closely correlated to work ability and employment status in systemic sclerosis. Rheumatology (Oxford). 2010;49(9):1739-1746. doi: 10.1093/rheumatology/keq145

12. Peres N, Morell-Dubois S, Hachulla E, Hatron PY, Duhamel A, Godard D, et al. Sclérodermie systémique et difficultés professionnelles : résultats d’une enquête prospective [Systemic sclerosis and occupational difficulties: Results of a prospective study]. Rev Med Interne. 2017;38(11):718-724 (In French). doi: 10.1016/j.revmed.2017.06.006

13. Nguyen C, Poiraudeau S, Mestre-Stanislas C, Rannou F, Bérezné A, Papelard A, et al. Employment status and socio-economic burden in systemic sclerosis: A cross-sectional survey. Rheumatology (Oxford). 2010;49(5):982-989. doi: 10.1093/rheumatology/kep400

14. Decuman S, Smith V, Verhaeghe S, Deschepper E, Vermeiren F, De Keyser F. Work participation and work transition in patients with systemic sclerosis: A cross-sectional study. Rheumatology (Oxford). 2012;51(2):297-304. doi: 10.1093/rheumatology/ker288

15. Krichevskaya OA, Vakulenko OYu, Goryachev DV, Erdes SF. Some approaches to quantitative evaluation of reduced productivity in subjects with rheumatic diseases. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2012;50(5):90-97 (In Russ.). doi: 10.14412/1995-4484-2012-1188

16. Cordeiro RA, Fischer FM, Shinjo SK. Systemic autoimmune diseases and work outcomes in Brazil: A scoping review. Rev Saude Publica. 2022;56:24. doi: 10.11606/s1518-8787.2022056003918

17. Vakulenko OYu, Krichevskaya OA, Goryachev DV, Erdes SF. Relation-ship of the clinical characteristics of rheumatoid arthritis to work capacity and efficiency. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2012;52(3):60-67 (In Russ.). doi: 10.14412/1995-4484-2012-711

18. Xavier RM, Zerbini CAF, Pollak DF, Morales-Torres JLA, Chalem P, Restrepo JFM, et al. Burden of rheumatoid arthritis on patients’ work productivity and quality of life. Adv Rheumatol. 2019;59(1):47. doi: 10.1186/s42358-019-0090-8

19. Podryadnova MV, Balabanova RM, Urumova MM, Erdes SF. Correlation between clinical characteristics of ankylosing spondylitis and work capacity and productivity. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2014;52(5):513-519 (In Russ.). doi: 10.14412/1995-4484-2014-513-519

20. Sağ S, Nas K, Sağ MS, Tekeoğlu İ, Kamanlı A. Relationship of work disability between the disease activity, depression and quality of life in patients with ankylosing spondylitis. J Back Musculoskelet Rehabil. 2018;31(3):499-505. doi: 10.3233/BMR-169657

21. Boonen A, Boone C, Albert A, Mielants H. Understanding limitations in at-work productivity in patients with active ankylosing spondylitis: The role of work-related contextual factors. J Rheumatol. 2015;42(1):93-100. doi: 10.3899/jrheum.131287

22. Scofield L, Reinlib L, Alarcón GS, Cooper GS. Employment and disability issues in systemic lupus erythematosus: A review. Arthritis Rheum. 2008;59(10):1475-1479. doi: 10.1002/art.24113

23. Baker K, Pope J. Employment and work disability in systemic lupus erythematosus: A systematic review. Rheumatology (Oxford). 2009;48(3):281-284. doi: 10.1093/rheumatology/ken477

24. Jetha A, Johnson SR, Gignac MAM. Unmet workplace support needs and lost productivity of workers with systemic sclerosis: A path analysis study. Arthritis Care Res (Hoboken). 2021;73(3):423-431. doi: 10.1002/acr.24123

25. Lerner D, Amick BC 3rd, Rogers WH, Malspeis S, Bungay K. The work limitations questionnaire. Med Care. 2001;39(1):72-85. doi: 10.1097/00005650-200101000-00009

26. Tang K, Beaton DE, Boonen A, Gignac MA, Bombardier C. Measures of work disability and productivity: Rheumatoid Arthritis Specific Work Productivity Survey (WPS-RA), Workplace Activity Limitations Scale (WALS), Work Instability Scale for Rheumatoid Arthritis (RA-WIS), Work Limitations Questionnaire (WLQ), and Work Productivity and Activity Impairment Questionnaire (WPAI). Arthritis Care Res (Hoboken). 2011;63(11):337-349. doi: 10.1002/acr.20633

27. Morrisroe K, Huq M, Stevens W, Rabusa C, Proudman SM, Nikpour M; and the Australian Scleroderma Interest Group (ASIG). Determinants of unemployment amongst Australian systemic sclerosis patients: Results from a multicentre cohort study. Clin Exp Rheumatol. 2016;34(Suppl 100(5)):79-84.

28. Bérezné A, Seror R, Morell-Dubois S, de Menthon M, Fois E, Dzeing-Ella A, et al. Impact of systemic sclerosis on occupational and professional activity with attention to patients with digital ulcers. Arthritis Care Res (Hoboken). 2011;63(2):277-285. doi: 10.1002/acr.20342

29. Steen VD, Medsger TA. The value of the Health Assessment Questionnaire and special patient-generated scales to demonstrate change in systemic sclerosis patients over time. Arthritis Rheum. 1997;40:1984-1991. doi: 10.1002/art.1780401110

30. Schnitzer M, Hudson M, Baron M, Steele R; Canadian Scleroderma Research Group. Disability in systemic sclerosis – A longitudinal observational study. J Rheumatol. 2011;38(4):685-692. doi: 10.3899/jrheum.100635

31. Jaeger VK, Distler O, Maurer B, Czirják L, Lóránd V. Functional disability and its predictors in systemic sclerosis: A study from the DeSScipher project within the EUSTAR group. Rheumatology (Oxford). 2018;57(3):441-450. doi: 10.1093/rheumatology/kex182

32. Valenzuela A, Baron M, Rodriguez-Reyna TS, Proudman S, Khanna D. Calcinosis is associated with ischemic manifestations and increased disability in patients with systemic sclerosis. Semin Arthritis Rheum. 2020;50(5):891-896. doi: 10.1016/j.semarthrit.2020.06.007

33. Guillevin L, Hunsche E, Denton CP, Krieg T, Schwierin B, Rosenberg D, et al.; DUO Registry Group. Functional impairment of systemic scleroderma patients with digital ulcerations: Results from the DUO Registry. Clin Exp Rheumatol. 2013;31(2 Suppl 76):71-80.

34. Castellví I, Eguiluz S, Escudero-Contreras A, Ríos JJ, Calvo-Alén J, Callejas-Rubio JL, et al.; LAUDES Study Group. LAUDES Study: Impact of digital ulcers on hand functional limitation, work productivity and daily activities, in systemic sclerosis patients. Rheumatol Int. 2019;39(11):1875-1882. doi: 10.1007/s00296-019-04436-z

35. Sharif R, Mayes MD, Nicassio PM, Gonzalez EB, Draeger H, McNearney TA, et al.; GENISOS Study Group. Determinants of work disability in patients with systemic sclerosis: A longitudinal study of the GENISOS cohort. Semin Arthritis Rheum. 2011;41(1):38-47. doi: 10.1016/j.semarthrit.2011.01.002

36. Poole JL, Anwar S, Mendelson C, Allaire S. Workplace barriers encountered by employed persons with systemic sclerosis. Work. 2016;55(4):923-929. doi: 10.3233/WOR-162448


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For citations:


Klimenko A.A., Mikheeva E.P., Shostak N.A., Demidova N.A. Work disability in systemic sclerosis – What is known? Rheumatology Science and Practice. 2023;61(6):672-677. (In Russ.) https://doi.org/10.47360/1995-4484-2023-672-677

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)