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Научно-практическая ревматология

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Волчаночный нефрит – современные аспекты диагностики и терапии. Часть I

https://doi.org/10.47360/1995-4484-2024-55-64

Аннотация

Волчаночный нефрит (ВН) по праву считается одним из наиболее частых среди тяжелых проявлений системной красной волчанки (СКВ); различные его клинические признаки встречаются не менее чем у 50% больных СКВ как в дебюте, так и на различных сроках болезни, а развитие ВН считается одним из наиболее важных предикторов смертности при СКВ. Среди различных его вариантов преобладает диффузный пролиферативный ВН с клинико-морфологическими признаками прогрессирования и быстрым развитием терминальной почечной недостаточности. Диагноз СКВ устанавливается на основании диагностических классификационных критериев Европейского альянса ревматологических ассоциаций/ Американской коллегии ревматологов (EULAR/ACR, European Alliance of Associations for Rheumatology/ American College of Rheumatology) 2019 г. Для подтверждения диагноза, оценки прогноза и выбора тактики лечения заболевания всем пациентам при отсутствии противопоказаний необходимо проведение биопсии почки. Помимо ВН, в спектр ассоциированных с СКВ вариантов поражения почек входят сосудистая патология, представленная тромботической микроангиопатией, волчаночной васкулопатией или васкулитом, тубулоинтерстициальное повреждение и волчаночная подоцитопатия.

Об авторах

С. К. Соловьев
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия

Соловьев Сергей Константинович

115522, Москва, Каширское шоссе, 34а



Н. Л. Козловская
ФГБОУ ВО «Московский государственный медико-стоматологический университет имени А.И. Евдокимова» Минздрава России
Россия

127473, Москва, ул. Делегатская, 20, стр. 1



Е. А. Асеева
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия

115522, Москва, Каширское шоссе, 34а



А. А. Баранов
ФГБОУ ВО «Ярославский государственный медицинский университет» Минздрава России
Россия

150000, Ярославль, ул. Революционная, 5



Н. Ю. Никишина
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия

115522, Москва, Каширское шоссе, 34а



Е. Л. Насонов
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»; ФГАОУ ВО «Первый Московский государственный медицинский университет имени И.М. Сеченова» Минздрава России (Сеченовский Университет)
Россия

115522, Москва, Каширское шоссе, 34а;

119991, Москва, ул. Трубецкая, 8, стр. 2



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Рецензия

Для цитирования:


Соловьев С.К., Козловская Н.Л., Асеева Е.А., Баранов А.А., Никишина Н.Ю., Насонов Е.Л. Волчаночный нефрит – современные аспекты диагностики и терапии. Часть I. Научно-практическая ревматология. 2024;62(1):55-64. https://doi.org/10.47360/1995-4484-2024-55-64

For citation:


Solovyev S.K., Kozlovskaya N.L., Aseeva E.A., Baranov A.A., Nikishina N.Yu., Nasonov E.L. Lupus nephritis – modern aspects of diagnosis and therapy. Part I. Rheumatology Science and Practice. 2024;62(1):55-64. (In Russ.) https://doi.org/10.47360/1995-4484-2024-55-64

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)