Acquired hemophilia in patient with Systemic lupus erythematosus: Clinical case report
https://doi.org/10.47360/1995-4484-2025-318-323
Abstract
Acquired hemophilia is a rare disease that develops because of the synthesis of antibodies to endogenous VIII blood clotting factor. The most common symptom of acquired hemophilia is spontaneous bleeding. Acquired hemophilia is observed more frequently in older population and in 50% is secondary to malignant tumors and autoimmune rheumatic diseases. In this article, we present a clinical case of autoimmune hemophilia that developed shortly before the onset of systemic lupus erythematosus.
About the Authors
S. A. Alekseeva
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Competing Interests:
Russian Federation
Sofya A. Alekseeva.
115522, Moscow, Kashirskoye Highway, 34A
Competing Interests:
None
N. I. Zozulya
National Medical Research Center for Hematology
Russian Federation
Competing Interests:
Russian Federation
Nadezhda I. Zozulya.
125167, Moscow, Novy Zykovsky road, 4
Competing Interests:
None
T. M. Reshetnyak
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
Competing Interests:
Russian Federation
Tatiana M. Reshetnyak.
115522, Moscow, Kashirskoye Highway, 34A
Competing Interests:
None
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For citations:
Alekseeva S.A., Zozulya N.I., Reshetnyak T.M. Acquired hemophilia in patient with Systemic lupus erythematosus: Clinical case report. Rheumatology Science and Practice. 2025;63(3):318-323. (In Russ.) https://doi.org/10.47360/1995-4484-2025-318-323
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