EVALUATION OF THE FUNCTIONAL STATUS OF THE RUSSIAN POPULATION OF PATIENTSWITH RHEUMATOID ARTHRITIS ACCORDING THE DATA OF THE RAiSeR STUDY

Objective. To evaluate the functional status of patients with rheumatoid arthritis (RA) in Russia, to compare the distribution and associations
between functional insufficiency (FI) and functional class (FC), as well as disability groups (DG), and to consider their impact of a
number of the patients' demographic, social, and clinic characteristics.
Methods. Rheumatologists from 27 cities and towns of Russia (a total of 30 centers) participated in the cross-sectional epidemiological study.
The study included all patients with valid rheumatoid arthritis, who had consecutively turned to a polyclinic rheumatologist or who had
been treated at hospital for 3 months. The demographic and social characteristics of a patient, his/her occupation, the onset and duration
of RA, DG and a reason for its receiving, and the patient's clinicofunctional status at the study were recorded.
Results. A total of 1504 patients, including 1271 women, were examined; their mean age was 53 years; the mean duration of the disease
was 10.5 years; 80.4% were seropositive for rheumatoid factor; 94.3% patients had erosive arthritis (X-ray stages II-IV RA). High disease
activity scores (DAS) were found; the mean DAS [Mean (SD)] was 5.44±1.18. Severe extraarticular manifestations were identified in 10%
of cases. 63% of the RA patients were in FC III and IV; 67% had grades 2 and 3 FI, and 44.5% had DGs I and II. An association was
found between FC and FI (r = 0.43; p < 0.0001), DG (r = -0.396; p<0.0001) and DAS28 (r = 0.42; p < 0.0001).
Conclusion. In the Russian population of patients with RA, half had high FC (III or IV). To determine the functional status and capabilities
of RA patients, it is expedient to use the rating methods Health Assessment Questionnaire (HAQ) and global functional status (in scores)
signifying the respective FC, which have acquired a high reputation among rheumatologists all over the world.

rheumatoid arthritis, functional insufficiency, functional classes, epidemiological study

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