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Научно-практическая ревматология

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ГРАНУЛЕМАТОЗ С ПОЛИАНГИИТОМ, ПАТОГЕНЕТИЧЕСКИ СВЯЗАННЫЙ С АНТИНЕЙТРОФИЛЬНЫМИ ЦИТОПЛАЗМАТИЧЕСКИМИ АНТИТЕЛАМИ: ОСОБЕННОСТИ КЛИНИЧЕСКОГО ТЕЧЕНИЯ

https://doi.org/10.14412/1995-4484-2012-1288

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Аннотация

На примере собственного опыта наблюдения 70 больных гранулематозом с полиангиитом (Вегенера) подробно изучены особенности течения клинических проявлений, отражающих гранулематозную воспалительную реакцию и некротизирующий полиангиит, проанализированы ранняя симптоматика, преморбидный фон, возможные провоцирующие факторы. Продемонстрировано, что гранулематозное воспаление и связанные с ним клинические проявления (в первую очередь псевдотумор орбиты и подскладочная гранулема гортани) с течением времени имеют тенденцию занимать доминирующее место в клинической картине заболевания, в то время как доля симптомов, условно относящихся к некротизирующему васкулиту, как правило, снижается. Расшифровка закономерностей развития гранулематоза с полиангиитом (Вегенера) может представлять ценность для дальнейшей разработки оптимальной лечебной стратегии.

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Для цитирования:


Beketova T.V. ГРАНУЛЕМАТОЗ С ПОЛИАНГИИТОМ, ПАТОГЕНЕТИЧЕСКИ СВЯЗАННЫЙ С АНТИНЕЙТРОФИЛЬНЫМИ ЦИТОПЛАЗМАТИЧЕСКИМИ АНТИТЕЛАМИ: ОСОБЕННОСТИ КЛИНИЧЕСКОГО ТЕЧЕНИЯ. Научно-практическая ревматология. 2012;50(6):19-28. https://doi.org/10.14412/1995-4484-2012-1288

For citation:


Beketova T.V. GRANULOMATOSIS WITH POLYANGIITIS, WHICH IS PATHOGENETICALLY ASSOCIATED WITH ANTINEUTROPHIL CYTOPLASMIC ANTIBODIES: CLINICAL FEATURES. Rheumatology Science and Practice. 2012;50(6):19-28. (In Russ.) https://doi.org/10.14412/1995-4484-2012-1288

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)