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Научно-практическая ревматология

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СОВРЕМЕННЫЙ ВЗГЛЯД НА БОЛЕЗНЬ ХОРТОНА: АНАЛИЗ СЛУЧАЕВ В ХАБАРОВСКОМ КРАЕ

https://doi.org/10.14412/1995-4484-2011-1459

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Аннотация

Цель проанализировать заболеваемость гигантоклеточным артритом (ГКА) в Хабаровском крае.

Материал и методы. Представлен анализ 10 случаев (11,6%) ГКА, выявленных в ходе 20-летнего проспективного наблюдения
и лечения
89 больных ревматической полимиалгией (РП) и ГКА. Определена частота отдельных диагностических критериев ГКА, описан дебют болезни, параклинические данные. В исследование были включены женщины в возрасте 67,3±2,1 [59; 76] года.

Результаты и обсуждение. Сочетание ГКА с РП отмечалось в 70% случаев. Помимо темпорального артериита наблюдалась клиническая картина поражения теменных (50%), глазных (30%), затылочных (30%), коронарных (10%) артерий. Поражение скальпа с образованием некроза теменной области выявлено в одном случае. Диагноз выставлен в среднем через 7,1±1,6 мес.
У всех отмечалось повышение СОЭ, в среднем до 110,2±3,1 по Вестергрену. 7 пациентов получали лечение преднизолоном 1,0 мг/кг массы тела, 3 больных (ввиду противопоказаний) – 0,5 мг/кг в сочетании с пульс-терапией циклофосфаном по 1000 мг внутривенно капельно один раз в месяц. Через 4 мес вследствие нарушения мозгового кровообращения умерла одна пациентка. В отдаленном периоде отмечено развитие остеопороза с переломами в двух случаях, у двух пациенток сахарный диабет и артериальная гипертензия, у одной больной рак шейки матки (успешно леченный). Потеря зрения наблюдалась у одной пациентки, диагноз которой был установлен спустя 1,5 года

Об авторах

Э. Н. Оттева
elvott@mail.ru


Т. Ю. Кочерова



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Для цитирования:


Оттева Э.Н., Кочерова Т.Ю. СОВРЕМЕННЫЙ ВЗГЛЯД НА БОЛЕЗНЬ ХОРТОНА: АНАЛИЗ СЛУЧАЕВ В ХАБАРОВСКОМ КРАЕ. Научно-практическая ревматология. 2011;49(5):38-45. https://doi.org/10.14412/1995-4484-2011-1459

For citation:


Otteva E.N., Kocherova T.Yu. CURRENT VIEW OF HORTON'S DISEASE: ANALYSIS OF ITS CASES IN THE KHABAROVSK TERRITORY. Rheumatology Science and Practice. 2011;49(5):38-45. (In Russ.) https://doi.org/10.14412/1995-4484-2011-1459

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)