MAGNETIC RESONANCE IMAGING DIAGNOSIS OF INFLAMMATORY CHANGES OF THE AXIAL SKELETON IN ANKYLOSING SPONDYLITIS
https://doi.org/10.14412/1995-4484-2016-53-59
Abstract
As of now, magnetic resonance imaging (MRI) ranks high in the early diagnosis of inflammatory changes in the musculoskeletal system. The uniqueness of MRI is that this diagnostic technique can detect the signs of active and inactive inflammation at the pre-radiological stage of the disease, i.e. before the onset of radiological symptoms of sacroiliitis and the formation of spinal syndesmophytes. At the same time there is evidence that there is a temporary association between active inflammation and the development of radiological changes in the joints.
The detection of bone marrow edema in the subchondral portions of bone tissue is of great importance not only for diagnosing the disease and verifying inflammatory activity, but also for predicting the development of chronic arthritis, choosing a treatment option, and evaluating the efficiency of performed therapy.
Based on their long-term experience, the authors provided explanations of the MRI pattern of active and inactive chronic sacroiliitis and spondylitis, which can considerably facilitate the early diagnosis of injury to the sacroiliac joints and vertebral column in patients with ankylosing spondylitis.
About the Authors
A. V. Smirnov
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
Sh. F. Erdes
V.A. Nasonova Research Institute of Rheumatology
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
Russian Federation
34A, Kashirskoe Shosse, Moscow 115522
References
1. Appel H, Loddenkemper C, Grozdanovic Z, et al. Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis. Arthritis Res Ther. 2006;8(5):R143. doi: 10.1186/ar2035
2. Baraliakos X, Listing J, Rudwaleit M, et al. The relationship between inflammation and new bone formation in patients with ankylosing spondylitis. Arthritis Res Ther. 2008;10(5):R104. doi: 10.1186/ar2496
3. Hermann K, Braun J, Fischer T, et al. Magnetic resonance tomography of sacroiliitis: anatomy, histological pathology, MRmorphology and grading. Radiology. 2004;44(3):217-28.
4. Maksymowych W, Chiowchanwisawakit T, Clare O, et al. Inflammatory lesions of the spine on magnetic resonance imaging predict the development of new syndesmophytes in ankylosing spondylitis. Arthritis Rheum. 2009;60(1):93-102. doi: 10.1002/art.24132
5. Oostveen J, Prevo R, den Boer J, et al. Early detection of sacroiliitis on magnetic resonance imaging and subsequent development of sacroiliitis on plain radiography: a prospective, longitudinal study. J Rheumatol. 1999;26:1953-8.
6. Bennett A, Marzo-Ortega H, Rehman A. The evidence for wholespine MRI in the assessment of axial spondyloarthropathy. Rheumatology. 2010;49:426-32. doi: 10.1093/rheumatology/kep427
7. Бочкова АГ, Левшакова АВ, Румянцева ОА и др. Магнитно-резонансная томография крестцово-подвздошных суставов у больных серонегативными спондилоартритами. Научно-практическая ревматология. 2007;(3);3-9 [Bochkova AG, Levshakova AV, Rumyantseva OA, et al. Magnetic resonance imaging of the sacroiliac joints in patients with seronegative spondyloarthritis. Nauchno-prakticheskaya revmatologiya = Rheumatology Science and Practice. 2007;(3);3-9 (In Russ.)].
8. Левшакова АВ, Бочкова АГ, Бунчук НВ. Структурные изменения позвоночника у больных анкилозирующим спондилитом. Медицинский вестник МВД. 2011;(2):32-5 [Levshakova AV, Bochkova AG, Bunchuk NV. Structural changes of the spine in patients with ankylosing spondylitis. Meditsinskii vestnik MVD. 2011;(2):32-5 (In Russ.)].
9. Baraliakos X, Landewer R, Hermann K-G, et al. Inflammation in ankylosing spondylitis: a systematic description of the extent and frequency of acute spinal changes using magnetic resonance imaging. Ann Rheum Dis. 2005;64:730-4. doi: 10.1136/ard.2004.029298
10. Sieper J, Rudwaleit M, Baraliakos X, et al. The Assessment of Spondyloarthritis International Society (ASAS) Handbook: a guide to assess spondyloarthritis. Ann Rheum Dis. 2009;68(Suppl. II):ii1-ii44. doi: 10.1136/ard.2008.104018
11. Левшакова АВ, Бочкова АГ, Бунчук НВ и др. Магнитно-резонансная томография в диагностике воспалительных изменений позвоночника у больных анкилозирующим спондилитом. Медицинская визуализация. 2010;(6):96-105 [Levshakova AV, Bochkova AG, Bunchuk NV, et al. Magnetic resonance imaging in the diagnosis of inflammatory changes of the spine in patients with ankylosing spondylitis. Meditsinskaya vizualizatsiya. 2010;(6):96-105 (In Russ.)].
12. Puhakka K, Jurik A, Schiotts-Christensen B, et al. MRI abnormalities of sacroiliac joints in early spondylarthropathy: a 1-year follow-up study. Scand J Rheumatol. 2004;33(5):332-8. doi: 10.1080/03009740410005881
13. Левшакова АВ, Бунчук НВ, Бочкова АГ и др. Структурные изменения крестцово-подвздошных суставов у больных анкилозирующим спондилитом по данным МРТ. Кубанский научный медицинский вестник. 2010;(1):70-4 [Levshakova AV, Bunchuk NV, Bochkova AG, et al. Structural changes in the sacroiliac joints in patients with ankylosing spondylitis by MRI. Kubanskii nauchnyi meditsinskii vestnik. 2010;(1):70-4 (In Russ.)].
14. Bollow M, Hermann K, Biedermann T, et al. Very early spondyloarthritis: where the inflammation in the sacroiliac joints starts. Ann Rheum Dis. 2005;64:1644-6. doi: 10.1136/ard.2004.034967
15. Braun J, Bollow M, Eggens U, et al. Use of dynamic magnetic resonance imaging with fast imaging in the detection of early and advanced sacroiliitis in spondyloarthropathy patients. Arthritis Rheum. 1994;37:1039-45. doi: 10.1002/art.1780370709
16. Hermann K, Althoff C, Schneider U, et al. Spinal changes in patients with spondyloarthritis: comparison of MR imaging and radiographic appearances. Radiographics. 2005;25(3):559-70. doi: 10.1148/rg.253045117
17. Bennett A, Rehman A, Hensor E, et al. The fatty Romanus lesion: a non-inflammatory spinal MRI lesion specific for axial spondyloarthropathy. Ann Rheum Dis. 2011;70(8):25-31.
Review
For citations:
Smirnov A.V., Erdes Sh.F. MAGNETIC RESONANCE IMAGING DIAGNOSIS OF INFLAMMATORY CHANGES OF THE AXIAL SKELETON IN ANKYLOSING SPONDYLITIS. Rheumatology Science and Practice. 2016;54(1):53-59. (In Russ.) https://doi.org/10.14412/1995-4484-2016-53-59
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