Развитие учения об аутовоспалительных заболеваниях в XXI в.
https://doi.org/10.14412/1995-4484-2018-5-18
Аннотация
В статье представлено развитие учения об аутовоспалительных заболеваниях (АВЗ) в последнее десятилетие. Изложены сведения об интерлейкине 1, инфламмасомах и их роли в развитии АВЗ, а также об интерферонопатиях и, в частности, протеасомных болезнях как новом классе аутовоспалительной патологии. Показано многообразие вариантов АВЗ, включая нозологии с доминированием поражения одной системы (кожа, кишечник, кости). Обсуждаются достижения в диагностике и оценке течения АВЗ. Показана взаимосвязь АВЗ с проблемами фундаментальной и клинической ревматологии.
Об авторах
Е. С. Фёдоров
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
С. О. Салугина
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
Н. Н. Кузьмина
ФГБНУ «Научно-исследовательский институт ревматологии им. В.А. Насоновой»
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
Россия
Москва, 115522 Москва, Каширское шоссе, 34А
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Рецензия
Для цитирования:
Фёдоров Е.С., Салугина С.О., Кузьмина Н.Н. Развитие учения об аутовоспалительных заболеваниях в XXI в. Научно-практическая ревматология. 2018;56:5-18. https://doi.org/10.14412/1995-4484-2018-5-18
For citation:
Fedorov E.S., Salugina S.O., Kuzmina N.N. Development of the doctrine of auto-inflammatory diseases in the XXI century. Rheumatology Science and Practice. 2018;56:5-18. (In Russ.) https://doi.org/10.14412/1995-4484-2018-5-18
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