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Trabecular bone score value in young men with ankylosing spondylitis

https://doi.org/10.47360/1995-4484-2022-460-464

Abstract

Aim – to investigate relationship of trabecular bone score (TBS) with activity and structural progression of ankylosing spondylitis (AS) in males younger than 50 years old without osteoporosis.

Materials and methods. 26 male AS patients took part in the investigation. AS activity was evaluated by BASDAI and ASDAS-CRP indices, and highly sensitive C-reactive protein level. Structural AS progression was evaluated by sacroiliitis (SI). TBS was evaluated using the double-energy X-ray absoptiometry. Correlation between clinical measures and TBS was obtained using the Spearman r-criterion for quantitative variables and Kendall’s τ coefficientfor qualitative variables.

Results. There was obtained no correlation between AS activity and TBS. Among clinical characteristics, SI stage was negatively correlated with TBS (τ=–0.313; p<0.05). Conclusion. TBS is associated with the severity of sacroiliitis in young AS male patients. Key words: ankylosing spondylitis, trabecular bone score, structural progression>˂ 0.05).

Conclusion. TBS is associated with the severity of sacroiliitis in young AS male patients. 

About the Authors

K. I. Kolpakov
Research Institute of Clinical and Experimental Lymphology – Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

630060, Novosibirsk, Timakova str., 2



E. A. Letyagina
Research Institute of Clinical and Experimental Lymphology – Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

630060, Novosibirsk, Timakova str., 2



V. O. Omelchenko
Research Institute of Clinical and Experimental Lymphology – Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

630060, Novosibirsk, Timakova str., 2



Yu. B. Ubshaeva
Research Institute of Clinical and Experimental Lymphology – Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

630060, Novosibirsk, Timakova str., 2



M. A. Korolev
Research Institute of Clinical and Experimental Lymphology – Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences
Russian Federation

630060, Novosibirsk, Timakova str., 2



References

1. Galushko EA, Nasonov EL. Prevalence of rheumatic diseases in Russia. Almanac of Clinical Medicine. 2018; 46(1):32-39 (In Russ.). doi: 10.18786/2072-0505-2018-46-1-32-39

2. Belaya ZE, Belova KYu, Biryukova EV, Dedov II, Dzeranova LK, Drapkina OM, et al. Federal clinical guidelines for diagnosis, treatment and prevention of osteoporosis. Osteoporosis and Bone Diseases. 2021;24(2):4-47 (In Russ.). doi: 10.14341/osteo12930

3. Poddubnyy D, Gaydukova I, Hermann KG, Song IH, Haibel H, Braun J, et al. Magnetic resonance imaging compared to conventional radiographs for detection of chronic structural changes in sacroiliac joints in axial spondyloarthritis. J Rheumatol. 2013;40(9):1557-1565. doi: 10.3899/jrheum.130141

4. Hebeisen M, Micheroli R, Scherer A, Baraliakos X, de Hooge M, van der Heijde D, et al. Spinal radiographic progression in axial spondyloarthritis and the impact of classification as nonradiographic versus radiographic disease: Data from the Swiss Clinical Quality Management cohort. PLoS One. 2020;15(3):e0230268. doi: 10.1371/journal.pone.0230268

5. Erdes S, Smirnov AV. Diagnostic technology for inflammatory changes in the skeleton with ankylosing spondylitis according to magnetic resonance imaging. Nauchno-PrakticheskayaRevmatologia = Rheumatology Science and Practice.2019;57(6):678-684 (In Russ.). doi: 10.14412/1995-4484-2019-678-684

6. Muschitz C, Kocijan R, Haschka J, Pahr D, Kaider A, Pietschmann P, et al. TBS reflects trabecular microarchitecture in premenopausal women and men with idiopathic osteoporosis and low-traumatic fractures. Bone. 2015;79:259-266. doi: 10.1016/j.bone.2015.06.007

7. Expert Panel on Musculoskeletal Imaging; Ward RJ, Roberts CC, Bencardino JT, Arnold E, Baccei SJ, Cassidy RC, et al. ACR Appropriateness Criteria Osteoporosis and Bone Mineral Density. J Am Coll Radiol. 2017;14(5S):S189-S202. doi: 10.1016/j.jacr.2017.02.018

8. Kolta S, Briot K, Fechtenbaum J, Paternotte S, Armbrecht G, Felsenberg D, et al. TBS result is not affected by lumbar spine osteoarthritis. Osteoporos Int. 2014;25(6):1759-1764. doi: 10.1007/s00198-014-2685-6

9. McCloskey EV, Odén A, Harvey NC, Leslie WD, Hans D, Johansson H, et al. A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX. J Bone Miner Res. 2016;31(5):940-948. doi: 10.1002/jbmr.2734

10. Kang KY, Goo HY, Park SH, Hong YS. Trabecular bone score as an assessment tool to identify the risk of osteoporosis in axial spondyloarthritis: A case-control study. Rheumatology (Oxford). 2018;57(3):462-469. doi: 10.1093/rheumatology/kex377

11. Kang KY, Chung MK, Kim HN, Hong YS, Ju JH, Park SH. Severity of sacroiliitis and erythrocyte sedimentation rate are associated with a low trabecular bone score in young male patients with ankylosing spondylitis. J Rheumatol. 2018;45(3):349-356. doi: 10.3899/jrheum.170079

12. Kim JW, Chung MK, Lee J, Kwok SK, Kim WU, Park SH, et al. Low bone mineral density of vertebral lateral projections can predict spinal radiographic damage in patients with ankylosing spondylitis. Clin Rheumatol. 2019;38(12):3567-3574. doi: 10.1007/s10067-019-04743-7

13. Wildberger L, Boyadzhieva V, Hans D, Stoilov N, Rashkov R, Aubry-Rozier B. Impact of lumbar syndesmophyte on bone health as assessed by bone density (BMD) and bone texture (TBS) in men with axial spondyloarthritis. Joint Bone Spine. 2017;84(4):463-466. doi: 10.1016/j.jbspin.2016.05.015

14. Kang KY, Ju JH, Park SH, Hong YS. Longitudinal association between trabecular bone loss and disease activity in axial spondyloarthritis: A 4-year prospective study. J Rheumatol. 2020;47(9):1330- 1337. doi: 10.3899/jrheum.190749

15. Jung JY, Han SH, Hong YS, Park SH, Ju JH, Kang KY. Inflammation on spinal magnetic resonance imaging is associated with poor bone quality in patients with ankylosing spondylitis. Mod Rheumatol. 2019;29(5):829-835. doi: 10.1080/14397595.2018.1510877

16. Kang KY, Jung JY, Lee SK, Min HK, Hong YS, Park SH, et al. Trabecular bone score value is associated with new bone formation independently of fat metaplasia on spinal magnetic resonance imaging in patients with ankylosing spondylitis. Scand J Rheumatol. 2020;49(4):292-300. doi: 10.1080/03009742.2019.1704053

17. Martineau P, Leslie WD. Trabecular bone score (TBS): Method and applications. Bone. 2017;104:66-72. doi: 10.1016/j.bone.2017.01.035

18. Cosman F, de Beur SJ, LeBoff MS, Lewiecki EM, Tanner B, Randall S, et al.; National Osteoporosis Foundation. Clinician’s guide to prevention and treatment of osteoporosis. Osteoporos Int. 2014;25(10):2359-2381. doi: 10.1007/s00198-014-2794-2

19. Krohn K, Schwartz EN, Chung YS, Lewiecki EM. Dual-energy X-ray absorptiometry monitoring with trabecular bone score: 2019 ISCD official position. J Clin Densitom. 2019;22(4):501-505. doi: 10.1016/j.jocd.2019.07.006

20. van der Heijde D, Ramiro S, Landewé R, Baraliakos X, Van den Bosch F, Sepriano A, et al. 2016 update of the ASASEULAR management recommendations for axial spondyloarthritis. Ann Rheum Dis. 2017;76(6):978-991. doi: 10.1136/annrheumdis-2016-210770


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For citations:


Kolpakov K.I., Letyagina E.A., Omelchenko V.O., Ubshaeva Yu.B., Korolev M.A. Trabecular bone score value in young men with ankylosing spondylitis. Rheumatology Science and Practice. 2022;60(4):460-464. (In Russ.) https://doi.org/10.47360/1995-4484-2022-460-464

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)