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New ACR/EULAR 2022 classification criteria for ANCA-associated vasculitis

https://doi.org/10.47360/1995-4484-2023-531-536

Abstract

The new 2022 classification criteria for antineutrophil cytoplasmic antibodies associated vasculitis (AAV), proposed by the American College of Rheumatology (ACR) and the European Alliance of Associations for Rheumatology (EULAR), was an important stage in the development of the doctrine of systemic vasculitis. Based on the analysis of large international cohorts, the criteria for granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis were revised, and classification criteria for microscopic polyangiitis were proposed for the first time. The creation’s history of the AAV classification criteria is discussed over the past three decades, and their limitations are considered. It should be noted, the ACR/EULAR 2022 criteria were developed for creating homogeneous groups of patients for scientific studies and cannot be widely used in clinical practice for the various AAV nosological forms diagnosis, primarily at early stage of the disease or mono organ damage (for example, kidneys). As before, decisive importance in AVV diagnostic belong to a detailed clinical analysis and a complete examination of patients to identify pathognomonic symptoms, including asymptomatic ones.

About the Author

T. V. Beketova
Central State Medical Academy of the Administrative Directorate of the President of the Russian Federation; V.A. Nasonova Research Institute of Rheumatology; Moscow Polytechnic University
Russian Federation

121359, Moscow, Marshala Timoshenko str., 19, building 1A 
115522, Moscow, Kashirskoye Highway, 34A 
107023, Moscow, Bolshaya Semyonovskaya str., 38



References

1. Jennette JC, Falk RJ, Bacon PA, Basu N, Cid MC, Ferrario F, et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65(1): 1-11. doi: 10.1002/art.37715

2. Leavitt RY, Fauci AS, Bloch DA, Michel BA, Hunder GG, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Wegener’s granulomatosis. Arthritis Rheum. 1990;33(8):1101-1107. doi: 10.1002/art.1780330807

3. Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP, et al. The American College of Rheumatology 1990 criteria for the classification of Churg – Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum. 1990;33(8):1094-1100. doi: 10.1002/art.1780330806

4. Watts R, Lane S, Hanslik T, Hauser T, Hellmich B, Koldingsnes W, et al. Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies. Ann Rheum Dis. 2007;66(2):222-227. doi: 10.1136/ard.2006.054593

5. Pierrot-Deseilligny Despujol C, Pouchot J, Pagnoux C, Coste J, Guillevin L. Predictors at diagnosis of a first Wegener’s granulomatosis relapse after obtaining complete remission. Rheumatology (Oxford). 2010;49(11):2181-2190. doi: 10.1093/rheumatology/keq244

6. Jennette JC, Falk RJ, Andrassy K, Bacon PA, Churg J, Gross WL, et al. Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis Rheum. 1994;37(2):187-192. doi: 10.1002/art.1780370206

7. Schönermarck U, Lamprecht P, Csernok E, Gross WL. Prevalence and spectrum of rheumatic diseases associated with proteinase 3-antineutrophil cytoplasmic antibodies (ANCA) and myeloperoxidase-ANCA. Rheumatology (Oxford). 2001;40(2):178-184. doi: 10.1093/rheumatology/40.2.178

8. Unizony S, Villarreal M, Miloslavsky EM, Lu N, Merkel PA, Spiera R, et al.; RAVE-ITN Research Group. Clinical outcomes of treatment of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis based on ANCA type. Ann Rheum Dis. 2016;75(6):1166-1169. doi: 10.1136/annrheumdis-2015-208073

9. Syed R, Rehman A, Valecha G, El-Sayegh S. Pauci-immune crescentic glomerulonephritis: An ANCA-associated vasculitis. Biomed Res Int. 2015;2015:402826. doi: 10.1155/2015/402826

10. Beketova TV, Frolova NF, Stolyarevich ES, Volkov MY, Kotenko ON, Aleksandrova EN. Problems in the diagnosis and treatment of ANCA-associated systemic vasculitis: In the focus of ANCA-negative pauci-immune glomerulonephritis. NauchnoPrakticheskaya Revmatologia = Rheumatology Science and Practice. 2016;54(5):543-552 (In Russ.). doi: 10.14412/1995-4484-2016-543-552

11. Eisenberger U, Fakhouri F, Vanhille P, Beaufils H, Mahr A, Guillevin L, et al. ANCA-negative pauci-immune renal vasculitis: Histology and outcome. Nephrol Dial Transplant. 2005;20(7):1392-1399. doi: 10.1093/ndt/gfh830

12. Finkielman JD, Lee AS, Hummel AM, Viss MA, Jacob GL, Homburger HA, et al.; WGET Research Group. ANCA are detectable in nearly all patients with active severe Wegener’s granulomatosis. Am J Med. 2007;120(7):643.e9-643.e14. doi: 10.1016/j.amjmed.2006.08.016

13. Chen LYC, Mattman A, Seidman MA, Carruthers MN. IgG4-related disease: What a hematologist needs to know. Haematologica. 2019;104(3):444-455. doi: 10.3324/haematol.2018.205526

14. Seeliger B, Sznajd J, Robson JC, Judge A, Craven A, Grayson PC, et al. Are the 1990 American College of Rheumatology vasculitis classification criteria still valid? Rheumatology (Oxford). 2017;56(7):1154-1161. doi: 10.1093/rheumatology/kex075

15. Watts RA, Suppiah R, Merkel PA, Luqmani R. Systemic vasculitis – Is it time to reclassify? Rheumatology (Oxford). 2011;50(4):643-645. doi: 10.1093/rheumatology/keq229

16. Basu N, Watts R, Bajema I, Baslund B, Bley T, Boers M, et al. EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis. Ann Rheum Dis. 2010;69(10):1744-1750. doi: 10.1136/ard.2009.119032

17. Robson JC, Grayson PC, Ponte C, Suppiah R, Craven A, Judge A, et al.; DCVAS Study Group. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis. Arthritis Rheumatol. 2022;74(3):393-399. doi: 10.1002/art.41986

18. Suppiah R, Robson JC, Grayson PC, Ponte C, Craven A, Khalid S, et al.; DCVAS Study Group. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis. Arthritis Rheumatol. 2022;74(3):400-406. doi: 10.1002/art.41983

19. Grayson PC, Ponte C, Suppiah R, Robson JC, Craven A, Judge A, et al.; DCVAS Study Group. 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for eosinophilic granulomatosis with polyangiitis. Arthritis Rheumatol. 2022;74(3):386-392. doi: 10.1002/art.41982

20. Beketova TV. Granulomatosis with polyangiitis, which is pathogenetically associated with antineutrophil cytoplasmic antibodies: clinical features. Nauchno-Prakticheskaya Revmatologia = Rheumatology Science and Practice. 2012;50(6):19-28 (In Russ.) doi: 10.14412/1995-4484-2012-1288


Review

For citations:


Beketova T.V. New ACR/EULAR 2022 classification criteria for ANCA-associated vasculitis. Rheumatology Science and Practice. 2023;61(5):531-536. (In Russ.) https://doi.org/10.47360/1995-4484-2023-531-536

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)