Clinical peculiarity of gout in South-Sakhalinsk residents

Abstract

Objective. To study gout prevalence and clinical features in South-Sakhalinsk residents. Methods. Clinical picture of gout was analyzed in 120 pts (117 male and 3 female) followed up in South-Sakhalinsk city rheumatological center from 1990 till 1999. There are 7% of Koreans among the South-Sakhalinsk residents. The rest are Slavs. Results. Prevalence and some clinical features of gout depend on pts nationality. Gout prevalence among Koreans (280:100000) is 5,2 times higher than among Slavs (54:100000). All Koreans pts were male. Male/female ratio among Slavs was 26/1. Typical gouty attacks were recorded in 54% of Slavs and in 93% of Koreans. Attack duration in Slavs usually was 7-10 days and mean attack number per year 2 while in Koreans 3-5 days and 4-5 per year respectively. Tophuses were present in 3% of Koreans and in 17% of Slavs. There were also considerable differences between groups on frequency of gouty internal organs damage and concomitant diseases. Conclusion. Ethnic features of population can modify clinical course and prevalence of the disease.