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RECURRENT ANCA-ASSOCIATED VASCULITIS AFTER KIDNEY ALLOTRANSPLANTATION

https://doi.org/10.14412/1995-4484-2016-105-107

Abstract

The paper describes a clinical case of recurrent microscopic polyangiitis diagnosed 10 years after kidney allotransplantation that was accompanied by the hyperproduction of antibodies to myeloperoxidase, graft damage with the morphological picture of pauci-immune extracapillary glomerulonephritis with crescents and other systemic manifestations, including interstitial lung injury complicated by hemoptysis. An effect is produced by biological anti-B-cell therapy with rituximab. The discussion involves the detailed review of the literature.

About the Authors

N. F. Frolova
City Polyclinic FiftyTwo, Moscow Healthcare Department
Russian Federation
7, Medynskaya St., Build. 1, Moscow 117546


L. Yu. Artyukhina
City Polyclinic FiftyTwo, Moscow Healthcare Department
Russian Federation
7, Medynskaya St., Build. 1, Moscow 117546


E. S. Stolyarevich
City Polyclinic FiftyTwo, Moscow Healthcare Department; Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia
Russian Federation

7, Medynskaya St., Build. 1, Moscow 117546;

1, Shchukinskaya St., Moscow 123182



References

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Review

For citations:


Frolova N.F., Artyukhina L.Yu., Stolyarevich E.S. RECURRENT ANCA-ASSOCIATED VASCULITIS AFTER KIDNEY ALLOTRANSPLANTATION. Rheumatology Science and Practice. 2016;54(1):105-107. (In Russ.) https://doi.org/10.14412/1995-4484-2016-105-107

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)