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Controversial issues of nomenclature and terminology of calcium pyrophosphate crystal deposition disease

https://doi.org/10.47360/1995-4484-2025-5-11

Abstract

Since the discovery in the early 1960s by D.J. McCarty crystals of calcium pyrophosphate in the synovial fluid of a patient with suspected gout, descriptions by D. Zitnan and S. Sitaj of radiological signs of cartilage calcification, and the subsequent appearance of the terms “pseudogout” and chondrocalcinosis, up to the present time, the issue of standardization of terms and concepts related to the disease of conditions and symptoms has not been resolved. The various alternative names of the disease and classification of phenotypes considered in the article should be the basis for creating a unified nomenclature of the disease of deposition of calcium pyrophosphate crystals, reflect the essence of the disease, and be understandable to doctors and patients.

About the Authors

M. S. Eliseev
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

Maxim S. Eliseev.

115522, Moscow, Kashirskoye Highway, 34A


Competing Interests:

None



E. L. Nasonov
V.A. Nasonova Research Institute of Rheumatology
Russian Federation

Evgeny L. Nasonov.

115522, Moscow, Kashirskoye Highway, 34A


Competing Interests:

None



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For citations:


Eliseev M.S., Nasonov E.L. Controversial issues of nomenclature and terminology of calcium pyrophosphate crystal deposition disease. Rheumatology Science and Practice. 2025;63(1):5-11. (In Russ.) https://doi.org/10.47360/1995-4484-2025-5-11

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ISSN 1995-4484 (Print)
ISSN 1995-4492 (Online)