SUBTYPES OF JUVENILE SYSTEMIC SCLERODERMA

Abstract

Aim: to allot clinical forms of juvenile systemic scleroderma (JSSD). Material and methods: investigation and dynamic observation of 60 patients aged 14-54 (mean age 25.1 ±7.2) with onset of disease in child's and adolescent’s ages from 1 to 16 years old ( in average 11. 4±3.8 year old) and disease duration from 1 to 39 years (in average 13.1 ±7.9). Results: 55% of patients demonstrated JSSD subtype with focal cutaneous lesion of different localization. The possibility of overlap-syndrome development in JSSD patients with onset in adolescent age typical for SSD-rheumatoid arthritis, SSD-polymvositis should be underlined. Conclusion: knowledge of different clinical forms and courses of the disease, modern diagnostics and early beginning of differential JSSD treatment will enable us to improve the prognosis and disease outcome.