Clinical efficacy of a new medical and prophylactic milk product for osteoporosis prophylaxis
https://doi.org/10.14412/1995-4484-2005-553
Abstract
Objective. To assess efficacy and safety of cheese paste (CP) enriched with calcium and vitamin D3 administered as medical and prophylactic product, an additional substance for prophylaxis and treatment of osteoporosis (OP). Material and methods. Randomized blind placebo-controlled study of CP efficacy was conducted in parallel groups. 100 menopausal women with osteopenia confirmed by bone densitometry were included (50 in the treatment group and 50 in the control group). The main stage of the study consisted of 5 visits lasted 12 months. Pain on visual analog scale, quality of life, serum 25(OH)-vitamin D level, markers of bone metabolism (osteocalcin and С-end telopeptides), spine and femur proximal part bone densitometry, thoracic and lumbar spine X-ray so as cases of new fractures registration were used as outcome measures. Results. The results of the study showed positive influence of CP enriched with calcium and vitamin D3 on spine bone mineral density, 25(OH)-vitamin D and С-end telopeptides levels.
References
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Review
For citations:
Ershova O.B., Belova K.Y., Konoplyanlk N.V. Clinical efficacy of a new medical and prophylactic milk product for osteoporosis prophylaxis. Rheumatology Science and Practice. 2005;43(1):31-35. (In Russ.) https://doi.org/10.14412/1995-4484-2005-553
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